Autoantigens in ITP

  • Yoshiaki TomiyamaEmail author


Antiplatelet autoantibodies play a critical role in autoimmune thrombocytopenia (ITP). Thus, characterization of autoantigens recognized by autoantibodies is a prerequisite for elucidating its pathophysiology. Platelet glycoprotein (GP) IIb-IIIa and/or GPIb-IX are the two major autoantigens in ITP. This capture reviews recent advance in the characterization and localization of autoantigens in ITP.


Autoimmune Hemolytic Anemia Direct Antiglobulin Test Platelet Destruction Autoimmune Thrombocytopenia Platelet Antigen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was supported by Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology in Japan and the Ministry of Health, Labour and Welfare in Japan.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  1. 1.Department of Blood TransfusionOsaka University HospitalSuitaJapan

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