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Autoimmune Thrombocytopenia　 pp 41–49Cite as

Epidemiology

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Abstract

ITP is estimated to have incidence between 2.16 and 3.9 per 100,000 person-years. There is a 1.1 to 1.5:1 female to male predominance in the entire ITP patients although ITP was more frequent among males in the age groups less than 5 years and over 75 years old. Intracranial hemorrhage (ICH) is the most devastating bleeding event, and its incidence is 0.37–0.6%. In contrast, recent studies suggest that ITP may have paradoxically an increased risk for thromboembolism. Regarding the treatment of ITP, the rate of splenectomy has been dramatically decreased to only 6% in recent years because patients are increasingly reluctant to undergo splenectomy and new drugs including anti-CD20 monoclonal antibody and thrombopoietin receptor agonists have been developed. Besides the bleeding risk, the infection risk derived from immunosuppressive treatment should be emphasized because bleeding and infection equally contributed to the death of ITP patients.

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Author information

Authors and Affiliations

  1. Division of Blood Transfusion and Cell Therapy, Ehime University Hospital, Toon, Ehime, 791-0295, Japan

    Takaaki Hato

  2. Shitennoji Hidenin Special Nursing Home for the Aged, 6-1-1 Gakuenmae, Habikino, Osaka, 583-0868, Japan

    Yoshiyuki Kurata

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  1. Takaaki Hato
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  2. Yoshiyuki Kurata
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Correspondence to Takaaki Hato .

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Editors and Affiliations

  1. Division of Hematology and Oncology Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka, Iwate, Japan

    Yoji Ishida

  2. Department of Blood Transfusion, Osaka University Hospital, Suita, Osaka, Japan

    Yoshiaki Tomiyama

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© 2017 Springer Nature Singapore Pte Ltd.

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Hato, T., Kurata, Y. (2017). Epidemiology. In: Ishida, Y., Tomiyama, Y. (eds) Autoimmune Thrombocytopenia　. Springer, Singapore. https://doi.org/10.1007/978-981-10-4142-6_4

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  • DOI: https://doi.org/10.1007/978-981-10-4142-6_4

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  • Online ISBN: 978-981-10-4142-6

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