Abstract
The aim of this study was produced silver nanoparticles using chemical reduction method and controlling size through pH variation. The nanoparticles had been characterized by studying their structural and morphological properties through UV-vis spectroscopy, atomic absorption spectroscopy, transmission electron microscopy and dynamic light scattering. Our results indicate that with the variation of pH levels can be obtained smaller silver nanoparticles. These nanoparticles could be evaluated as antimicrobial agents for potential use as a barrier control of hospital acquired infections.
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References
Centers for Disease Control and Prevention. Healthcare associated infections [Internet]. Atlanta: Centers for Disease Control and Prevention; 2016 Mar [cited 2016 Jun 14]. Available form: http://www.cdc.gov/hai/
World Health Organization. The burden of health care-associated infection worldwide [Internet]. Geneva: World Health Organization; cited [2016 Jun 14]. Available from: http://www.who.int/gpsc/country_work/burden_hcai/en/.
Pan American Health Organization, World Health Organization. Antimicrobial resistance [Internet]. Geneva: World Health Organization; cited [2016 Jun 14]. Available from: http://www.paho.org/hq/index.php?option=com_topics&view=article&id=7&Itemid=40740&lang=en.
World Economic Forum. The Global Risks Report 2016 [Internet]. cited [2016 Jun 14]. Available from: http://www.weforum.org/reports/the-global-risks-report-2016.
Huh AJ, Kwon YJ (2011) “Nanoantibiotics”: a new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era. J Control Release 2:128–145.
Pelgrift RY, Friedman AJ (2013) Nanotechnology as a therapeutic tool to combat microbial resistance. Adv Drug Deliv Rev 13–14:1803–1815.
Brown AN, Smith K, Samuels TA et al (2012) Nanoparticles functionalized with ampicillin destroy multiple-antibiotic-resistant isolates of Pseudomonas aeruginosa and Enterobacter aerogenes and methicillin-resistant Staphylococcus aureus. Appl Environ Microbiol 8:2768–2774.
Ajitha B, Ashok Kumar Reddy Y, Sreedhara Reddy P (2015) Enhanced antimicrobial activity of silver nanoparticles with controlled particle size by pH variation. Powder Technol 269:110–117.
Guzman M, Dille J, Godet S (2012) Synthesis and antibacterial activity of silver nanoparticles against gram-positive and gram-negative bacteria. Nanomedicine Nanotechnol Biol Med 1:37–45.
Pal S, Tak YK, Song JM (2007) Does the Antibacterial Activity of Silver Nanoparticles Depend on the Shape of the Nanoparticle? A Study of the Gram-Negative Bacterium Escherichia coli. Appl Environ Microbiol 6:1712–1720.
Martínez-Castañón GA, Niño-Martínez N, Martínez-Gutierrez F et al (2008) Synthesis and antibacterial activity of silver nanoparticles with different sizes. J Nanoparticle Res 8:1343–1348.
Kim JS, Kuk E, Yu KN et al (2007) Antimicrobial effects of silver nanoparticles. Nanomedicine Nanotechnol Biol Med 1:95–101.
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Zapata-Giraldo, J. et al. (2017). Characterization of silver nanoparticles for potential use as antimicrobial agent. In: Torres, I., Bustamante, J., Sierra, D. (eds) VII Latin American Congress on Biomedical Engineering CLAIB 2016, Bucaramanga, Santander, Colombia, October 26th -28th, 2016. IFMBE Proceedings, vol 60. Springer, Singapore. https://doi.org/10.1007/978-981-10-4086-3_62
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DOI: https://doi.org/10.1007/978-981-10-4086-3_62
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