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Sexually Transmitted Infections in Males

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Abstract

  • Causative organisms, pathogenesis and clinical features of sexually transmitted infections

  • Principles of diagnostic evaluation and management

The older terminology of ‘venereal disease’ has over the past few decades been superseded by ‘sexually transmitted diseases’ (STDs). The term sexually transmitted infections (STIs) has replaced the STDs because many sexually transmitted infections remain asymptomatic and do not cause any disease.

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References

  • Albritton WL. Biology of Haemophilus ducreyi. Microbiol Rev. 1989;53:377–89.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Ashley RL. Laboratory techniques in the diagnosis of herpes simplex infection. Genitourin Med. 1993;69:174–83.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Bai Y, Xue H, Wang K, Cai L, Qiu J, Bi S, et al. Covalent fusion inhibitors targeting HIV-1 gp41 deep pocket. Amino Acids. 2013;44(2):701–13.

    Article  CAS  PubMed  Google Scholar 

  • Benedetti J, Corey L, Ashley R. Recurrence rates in genital herpes after symptomatic first-episode infection. Ann Intern Med. 1994;121:847–54.

    Article  CAS  PubMed  Google Scholar 

  • Berger RE. Acute epididymitis. Sex Transm Dis. 1981;8:286–9.

    Article  CAS  PubMed  Google Scholar 

  • Bignell C, Unemo M. 2012 European guideline on the diagnosis and treatment of gonorrhoea in adults. Int J STD AIDS. 2013;24:85–92.

    Article  CAS  PubMed  Google Scholar 

  • Burd EM. Human papillomavirus laboratory testing: the changing paradigm. Clin Microbiol Rev. 2016;29:291–319.

    Article  PubMed  PubMed Central  Google Scholar 

  • Carter JS, Kemp DJ. A colorimetric detection system for Calymmatobacterium granulomatis. Sex Transm Infect. 2000;76:134–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cherneskey MA. Chlamydia trachomatis diagnostics. Sex Transm Infect. 2002;78:232–4.

    Article  Google Scholar 

  • Corey L, Adams HG, Brown ZA, Holmes KK. Genital herpes simplex virus infections: clinical manifestations, course, and complications. Ann Intern Med. 1983;98:958–72.

    Article  CAS  PubMed  Google Scholar 

  • D’Aunoy R, von Haam E. General reviews: venereal lymphogranuloma. Arch Pathol. 1939;27:1032–82.

    Google Scholar 

  • Das K, Arnold E. HIV-1 reverse transcriptase and antiviral drug resistance. Part 1. Curr Opin Virol. 2013;3(2):111–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Deeks SG. The end of AIDS: HIV infection as a chronic disease. Lancet. 2013;382(9903):1525–33.

    Article  PubMed  PubMed Central  Google Scholar 

  • Dyson N, Howley PM, Munger K, Harlow E. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science. 1989;243:934–7.

    Article  CAS  PubMed  Google Scholar 

  • Engelkens HJ, ten Kate FJ, Vuzevski VD, van der Sluis JJ, Stolz E. Primary and secondary syphilis: a histopathological study. Int J STD AIDS. 1991;2:280–4.

    Article  CAS  PubMed  Google Scholar 

  • Grünewald K, Desai P, Winkler DC, Heymann JB, Belnap DM, Baumeister W, et al. Three-dimensional structure of herpes simplex virus from cryo-electron tomography. Science. 2003;302:1396–8.

    Article  PubMed  Google Scholar 

  • Hart G. Donovanosis. Clin Infect Dis. 1997;25:24–30.

    Article  CAS  PubMed  Google Scholar 

  • Hatch TP. Developmental biology. In: Stephens RS, editor. Chlamydia: intracellular biology, pathogenesis and immunity. Washington, DC: ASM Press; 1999. p. 29–67.

    Chapter  Google Scholar 

  • Holmes KK, Handsfield HH, Wang SP, Wenworth BB, Turck M, Anderson JB, et al. Etiology of nongonococcal urethritis. N Engl J Med. 1975;292:1199–205.

    Article  CAS  PubMed  Google Scholar 

  • Howles JK. Synopsis of clinical syphilis. St.Louis: The C. V. Mosby Co; 1943.

    Google Scholar 

  • Hurwitz DJ, Pincus L, Kupper TS. Imiquimod: a topically applied link between innate and acquired immunity. Arch Dermatol. 2003;139:1347–50.

    Article  PubMed  Google Scholar 

  • Jacobs Jr NF, Kraus SJ. Gonococcal and nongonococcal urethritis in men: clinical and laboratory differentiation. Ann Intern Med. 1975;82:7–12.

    Article  CAS  PubMed  Google Scholar 

  • Kallstrom H, Liszewski MK, Atkinson JP, Jonsson AB. Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria. Mol Microbiol. 1997;25:639–47.

    Article  CAS  PubMed  Google Scholar 

  • Lafferty WE, Coombs RW, Benedetti J, Critchlow C, Corey L. Recurrences after oral and genital herpes simplex virus infection. Influence of site of infection and viral type. N Engl J Med. 1987;4(316):1444–9.

    Article  Google Scholar 

  • Larsen SA, Steiner BM, Rudolph AH. Laboratory diagnosis and interpretation of tests for syphilis. Clin Microbiol Rev. 1995;8:1–21.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Lewis DA. Chancroid: clinical manifestations, diagnosis, and management. Sex Transm Infect. 2003;79:68–71.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lieberman-Blum SS, Fung HB, Bandres JC. Maraviroc: A CCR5-receptor antagonist for the treatment of HIV-1 infection. Clin Ther. 2008;30(7):1228–50.

    Article  CAS  PubMed  Google Scholar 

  • Maartens G. HIV infection: epidemiology, pathogenesis, treatment and prevention. Lancet. 2014;384:258–71.

    Article  PubMed  Google Scholar 

  • Merz AJ, So M. Interactions of pathogenic Neisseriae with epithelial cell membranes. Annu Rev Cell Dev Biol. 2000;16:423–57.

    Article  CAS  PubMed  Google Scholar 

  • Metifiot M, Marchand C, Pommier Y. HIV integrase inhibitors: 20 years landmark and challenges. Adv Pharmacol. 2013;67:75–105.

    Article  CAS  PubMed  Google Scholar 

  • Mindel A, Tovey SJ, Timmins DJ, Williams P. Primary and secondary syphilis, 20 years’ experience. 2. Clinical features. Genitourin Med. 1989;65:1–3.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Norris SJ, Larsen SA. Treponema and other host-associated spirochetes. In: Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH, editors. Manual of clinical microbiology. 6th ed. Washington, D.C: ASM Press; 1995. p. 636–51.

    Google Scholar 

  • Okagaki T. Impact of human papillomavirus research on the histopathologic concepts of genital neoplasms. Curr Top Pathol. 1992;85:273–307.

    Article  CAS  PubMed  Google Scholar 

  • Oriel JD. Natural history of genital warts. Br J Vener Dis. 1971;47:1–13.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Orle KA, Gates CA, Martin DH, Body BA, Weiss JB. Simultaneous PCR detection of Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus types 1 and 2 from genital ulcers. J Clin Microbiol. 1996;34:49–54.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Palefsky JM, Holly EA, Ralston ML, Jay N. Prevalence and risk factors for human papillomavirus infection of the anal canal in human immunodeficiency virus (HIV)-positive and HIV-negative homosexual men. J Infect Dis. 1998;177:361–7.

    Article  CAS  PubMed  Google Scholar 

  • Parekh BS, Ellenberger D, Westerman L, Yang C, Nkengasong JN. Human immunodeficiency virus (HIV) infections. In: Unemo M (editor in chief), Ballard R, Ison C, Lewis D, Ndowa F, Peeling R, editors. Laboratory diagnosis of sexually transmitted infections, including human immunodeficiency virus 2013. WHO Document Production Services, Geneva; 2013. p.155–166.

    Google Scholar 

  • Pund ER, Greenblatt RB. Specific histology of granuloma inguinale. Arch Pathol. 1937;23:224–9.

    Google Scholar 

  • Rahman MU, Hudson AP, Schumacher Jr HR. Chlamydia and Reiter’s syndrome (reactive arthritis). Rheum Dis Clin North Am. 1992;18:67–79.

    CAS  PubMed  Google Scholar 

  • Reeves WC, Corey L, Adams HG, Vontver LA, Holmes KK. Risk of recurrence after first episodes of genital herpes: relation to HSV type and antibody response. N Engl J Med. 1981;305:315–9.

    Article  CAS  PubMed  Google Scholar 

  • Richens J. The diagnosis and treatment of donovanosis (granuloma inguinale). Genitourin Med. 1991;67:441–52.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Satterwhite CL, Torrone E, Meites E, Dunne EF, Mahajan R, Ocfemia MC, et al. Sexually transmitted infections among US women and men: prevalence and incidence estimates , 2008. Sex Transm Dis. 2013;40(3):187–93.

    Article  PubMed  Google Scholar 

  • Schachter J, Dawson CR. Human chlamydial infections. Littleton: PSG Publishing; 1978. p. 45–62.

    Google Scholar 

  • Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell. 1990;63:1129–36.

    Article  CAS  PubMed  Google Scholar 

  • Singh A, Preiksaitis J, Ferenczy A, Romanowski B. The laboratory diagnosis of herpes simplex virus infections. Can J Infect Dis Med Microbiol. 2005;16:92–8.

    PubMed  PubMed Central  Google Scholar 

  • Stamm WE, Guinan ME, Johnson C, Starcher T, Holmes KK, McCormack WM. Effect of treatment regimens for Neisseria gonorrhoeae on simultaneous infection with Chlamydia trachomatis. N Engl J Med. 1984;310:545–9.

    Article  CAS  PubMed  Google Scholar 

  • Stokes JH, Beerman H, Ingraham NR. Modern clinical syphilology. Philadelphia: The W. B. Saunders Co; 1944.

    Google Scholar 

  • Uyeda CT, Welborn P, Ellison-Birang N, Shunk K, Tsaouse B. Rapid diagnosis of chlamydial infections with the MicroTrak direct test. J Clin Microbiol. 1984;20:948–50.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Watsford SD, Alderman LW. Granuloma inguinale. Med J Aust. 1953;2:50–2.

    CAS  PubMed  Google Scholar 

  • Wensing AM, van Maarseveen NM, Nijhuis M. Fifteen years of HIV protease inhibitors: raising the barrier to resistance. Antiviral Res. 2010;85(1):59–74.

    Article  CAS  PubMed  Google Scholar 

  • WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults and children. Geneva, World Health Organization; 2007. http://www.who.int/hiv/pub/guidelines/HIVstaging150307.pdf. Accessed on 4 Aug 2016.

  • Workowski KA, Bolan GA. Sexually transmitted diseases treatment guidelines, 2015. MMWR. 2015;64(3):1–134.

    PubMed  Google Scholar 

  • zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer. 2002;2:342–50.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Microbiology, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, India

    Mohit Agrawal MD & Ashok Rattan MD, MAMS

Authors
  1. Mohit Agrawal MD
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  2. Ashok Rattan MD, MAMS
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Correspondence to Ashok Rattan MD, MAMS .

Editor information

Editors and Affiliations

  1. Department of Reproductive Biology, All India Institute of Medical Sciences, New Delhi, India

    Anand Kumar

  2. Department of Reproductive Biology, All India Institute of Medical Sciences, New Delhi, India

    Mona Sharma

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Agrawal, M., Rattan, A. (2017). Sexually Transmitted Infections in Males. In: Kumar, A., Sharma, M. (eds) Basics of Human Andrology. Springer, Singapore. https://doi.org/10.1007/978-981-10-3695-8_27

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