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Spermatogenesis

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Basics of Human Andrology

Abstract

  • Stages of spermatogenesis

  • Spermatogenic wave and cycle

  • Male germ cell apoptosis

  • Factors regulating spermatogenesis

  • Effects of endocrine disruptors on spermatogenesis

  • Genetic disorders of spermatogenesis

Spermatogenesis is a complex cellular event which is divided into four distinct steps, namely, (1) mitotic proliferation of spermatogonial cells; (2) meiotic division to yield four haploid, round spermatids; (3) spermiogenesis process which leads to transformation of round spermatids to elongated spermatids; and (4) spermiation process that causes release of mature sperm into tubular lumen. Various types of spermatogenic cells are shown in Fig. 10.1. In humans, it takes an average of 74 days for a primordial germ cell to transform into a mature sperm (Gilbert 2000).

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Correspondence to Anand Kumar MD, FAMS .

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Dhole, B., Kumar, A. (2017). Spermatogenesis. In: Kumar, A., Sharma, M. (eds) Basics of Human Andrology. Springer, Singapore. https://doi.org/10.1007/978-981-10-3695-8_10

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