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Bone marrow stem cell therapy for stroke pp 311–332Cite as

Imaging and Tracking Transplanted Bone Marrow Stem Cells After Stroke

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Abstract

Stem cells provide a promising therapy for treating stroke. Several imaging techniques provide the possibility of the visual representation of biological processes of transplanted stem cells in vivo. Further means of monitoring the transplanted cells safely, noninvasively, and longitudinally would contribute to the understanding of the underlying stem cell therapeutic mechanism. In this chapter, we describe the state-of-the-art methods of monitoring transplanted stem cells in vivo, including magnetic resonance imaging (MRI), radionuclide imaging, and optical imaging. Their principles vary and each has advantages and drawbacks. Presently, no single technique is excellent through ideal criteria; the combination of multiple imaging modalities is thus an attractive strategy.

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Author information

Authors and Affiliations

  1. Department of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China

    Hongbin Han & Wei Wang

  2. Beijing Key Laboratory of Magnetic Resonance Imaging Device and Technique, Beijing, 100191, China

    Hongbin Han & Wei Wang

  3. Nuclear Medicine Department, Peking University Third Hospital, 49 Huayuanbei Road, Haidian District, Beijing, China, 100083

    Weifang Zhang

  4. Medical and Health Analysis Center, Peking University, 38 Xueyuan Road, Haidian District, Beijing, China, 100083

    Lan Yuan & Yunqian Li

  5. Department of Anatomy and Embryology, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing, China, 100083

    Junhao Yan

  6. Department of Radiology, Beijing An Zhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Disease, Anzhen Road 2th, Chaoyang district, Beijing, China

    Chunyan Shi

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  1. Hongbin Han
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  2. Weifang Zhang
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  3. Lan Yuan
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  4. Junhao Yan
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  5. Wei Wang
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  6. Chunyan Shi
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  7. Yunqian Li
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Correspondence to Hongbin Han .

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Editors and Affiliations

  1. Department of Pharmacology Neuroscience, University of North Texas Health Science Center, Fort Worth, Texas, USA

    Kunlin Jin

  2. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, Beijing, China

    Xunming Ji

  3. Department of Neurosurgery First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China

    Qichuan Zhuge

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Han, H. et al. (2017). Imaging and Tracking Transplanted Bone Marrow Stem Cells After Stroke. In: Jin, K., Ji, X., Zhuge, Q. (eds) Bone marrow stem cell therapy for stroke. Springer, Singapore. https://doi.org/10.1007/978-981-10-2929-5_14

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