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Clinical Evidence of Intravascular Ultrasound-Guided Percutaneous Coronary Intervention

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Coronary Imaging and Physiology

Abstract

Intravascular ultrasound (IVUS) provides anatomic information regarding the coronary artery lumen, wall, and plaques, which can help the accurate evaluation of lesion characteristics with vessel sizing. In addition, after stent implantation, underexpansion, malapposition, or edge dissections can be detected by IVUS. Thus, through further intervention based on these IVUS findings, stent optimization can be achieved, causing the improved clinical outcomes. Current guidelines recommend the use of IVUS to optimize stent implantation for select patients (Class of recommendation IIa, Level of evidence B) [1, 2]. However, recently, many evidences demonstrating the clinical usefulness of IVUS have been accumulated since the prior guidelines were released. In this chapter, clinical evidences of IVUS-guided percutaneous coronary intervention (PCI) will be discussed from observational studies, randomized studies, and meta-analysis.

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References

  1. Levine GN, Bates ER, Blankenship JC, et al. 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention. A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines and the society for cardiovascular angiography and interventions. J Am Coll Cardiol. 2011;58:e44–122.

    Article  PubMed  Google Scholar 

  2. Windecker S, Kolh P, Alfonso F, et al. 2014 ESC/EACTS guidelines on myocardial revascularization: the task force on myocardial revascularization of the European society of cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J. 2014;35:2541–619.

    Article  PubMed  Google Scholar 

  3. Jakabcin J, Spacek R, Bystron M, et al. Long-term health outcome and mortality evaluation after invasive coronary treatment using drug eluting stents with or without the ivus guidance. Randomized control trial. HOME DES IVUS. Catheter Cardiovasc Interv. 2010;75:578–83.

    Article  PubMed  Google Scholar 

  4. Chieffo A, Latib A, Caussin C, et al. A prospective, randomized trial of intravascular-ultrasound guided compared to angiography guided stent implantation in complex coronary lesions: the AVIO trial. Am Heart J. 2013;165:65–72.

    Article  PubMed  Google Scholar 

  5. Kim JS, Kang TS, Mintz GS, et al. Randomized comparison of clinical outcomes between intravascular ultrasound and angiography-guided drug-eluting stent implantation for long coronary artery stenoses. JACC Cardiovasc Interv. 2013;6:369–76.

    Article  PubMed  Google Scholar 

  6. Mariani J Jr, Guedes C, Soares P, et al. Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (minimizing contrast utilization with ivus guidance in coronary angioplasty) randomized controlled trial. JACC Cardiovasc Interv. 2014;7:1287–93.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Tan Q, Wang Q, Liu D, et al. Intravascular ultrasound-guided unprotected left main coronary artery stenting in the elderly. Saudi Med J. 2015;36:549–53.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Kim BK, Shin DH, Hong MK, et al. Clinical impact of intravascular ultrasound-guided chronic total occlusion intervention with zotarolimus-eluting versus biolimus-eluting stent implantation: randomized study. Circ Cardiovasc Interv. 2015;8:e002592.

    Article  PubMed  Google Scholar 

  9. Tian NL, Gami SK, Ye F, et al. Angiographic and clinical comparisons of intravascular ultrasound- versus angiography-guided drug-eluting stent implantation for patients with chronic total occlusion lesions: two-year results from a randomised AIR-CTO study. EuroIntervention. 2015;10:1409–17.

    Article  PubMed  Google Scholar 

  10. Hong SJ, Kim BK, Shin DH, et al. Effect of intravascular ultrasound-guided vs angiography-guided everolimus-eluting stent implantation: the ivus-xpl randomized clinical trial. JAMA. 2015;314:2155–63.

    Article  CAS  PubMed  Google Scholar 

  11. Witzenbichler B, Maehara A, Weisz G, et al. Relationship between intravascular ultrasound guidance and clinical outcomes after drug-eluting stents: the assessment of dual antiplatelet therapy with drug-eluting stents (ADAPT-DES) study. Circulation. 2014;129:463–70.

    Article  CAS  PubMed  Google Scholar 

  12. Roy P, Steinberg DH, Sushinsky SJ, et al. The potential clinical utility of intravascular ultrasound guidance in patients undergoing percutaneous coronary intervention with drug-eluting stents. Eur Heart J. 2008;29:1851–7.

    Article  CAS  PubMed  Google Scholar 

  13. Park KW, Kang SH, Yang HM, et al. Impact of intravascular ultrasound guidance in routine percutaneous coronary intervention for conventional lesions: data from the EXCELLENT trial. Int J Cardiol. 2013;167:721–6.

    Article  PubMed  Google Scholar 

  14. Youn YJ, Yoon J, Lee JW, et al. Intravascular ultrasound-guided primary percutaneous coronary intervention with drug-eluting stent implantation in patients with ST-segment elevation myocardial infarction. Clin Cardiol. 2011;34:706–13.

    Article  PubMed  Google Scholar 

  15. Kim JS, Hong MK, Ko YG, Choi D, Yoon JH, Choi SH, Hahn JY, Gwon HC, Jeong MH, Kim HS, Seong IW, Yang JY, Rha SW, Tahk SJ, Seung KB, Park SJ, Jang Y. Impact of intravascular ultrasound guidance on long-term clinical outcomes in patients treated with drug-eluting stent for bifurcation lesions: data from a korean multicenter bifurcation registry. Am Heart J. 2011;161:180–7.

    Article  CAS  PubMed  Google Scholar 

  16. Hong SJ, Kim BK, Shin DH, et al. Usefulness of intravascular ultrasound guidance in percutaneous coronary intervention with second-generation drug-eluting stents for chronic total occlusions (from the multicenter Korean-chronic total occlusion registry). Am J Cardiol. 2014;114:534–40.

    Article  PubMed  Google Scholar 

  17. de la Torre Hernandez JM, Baz Alonso JA, Gomez Hospital JA, et al. Clinical impact of intravascular ultrasound guidance in drug-eluting stent implantation for unprotected left main coronary disease: pooled analysis at the patient-level of 4 registries. JACC Cardiovasc Interv. 2014;7:244–54.

    Article  PubMed  Google Scholar 

  18. Jang JS, Song YJ, Kang W, et al. Intravascular ultrasound-guided implantation of drug-eluting stents to improve outcome: a meta-analysis. JACC Cardiovasc Interv. 2014;7:233–43.

    Article  PubMed  Google Scholar 

  19. Ahn JM, Kang SJ, Yoon SH, et al. Meta-analysis of outcomes after intravascular ultrasound-guided versus angiography-guided drug-eluting stent implantation in 26,503 patients enrolled in three randomized trials and 14 observational studies. Am J Cardiol. 2014;113:1338–47.

    Article  PubMed  Google Scholar 

  20. Elgendy IY, Mahmoud AN, Elgendy AY, et al. Outcomes with intravascular ultrasound-guided stent implantation: a meta-analysis of randomized trials in the era of drug-eluting stents. Circ Cardiovas Interv. 2016;9:e003700.

    Article  CAS  Google Scholar 

  21. Steinvil A, Zhang YJ, Lee SY, et al. Intravascular ultrasound-guided drug-eluting stent implantation: an updated meta-analysis of randomized control trials and observational studies. Int J Cardiol. 2016;216:133–9.

    Article  PubMed  Google Scholar 

  22. Shin DH, Hong SJ, Mintz GS, et al. Effects of intravascular ultrasound-guided versus angiography-guided new-generation drug-eluting stent implantation: meta-analysis with individual patient-level data from 2,345 randomized patients. JACC Cardiovasc Interv. 2016;9:2232.

    Article  PubMed  Google Scholar 

  23. Park SJ, Ahn JM, Kang SJ, et al. Intravascular ultrasound-derived minimal lumen area criteria for functionally significant left main coronary artery stenosis. JACC Cardiovasc Interv. 2014;7:868–74.

    Article  PubMed  Google Scholar 

  24. Jasti V, Ivan E, Yalamanchili V, et al. Correlations between fractional flow reserve and intravascular ultrasound in patients with an ambiguous left main coronary artery stenosis. Circulation. 2004;110:2831–6.

    Article  PubMed  Google Scholar 

  25. Kang SJ, Lee JY, Ahn JM, et al. Intravascular ultrasound-derived predictors for fractional flow reserve in intermediate left main disease. JACC Cardiovasc Interv. 2011;4:1168–74.

    Article  PubMed  Google Scholar 

  26. Kang SJ, Ahn JM, Song H, et al. Comprehensive intravascular ultrasound assessment of stent area and its impact on restenosis and adverse cardiac events in 403 patients with unprotected left main disease. Circ Cardiovasc Interv. 2011;4:562–9.

    Article  PubMed  Google Scholar 

  27. Patel Y, Depta JP, Novak E, et al. Long-term outcomes with use of intravascular ultrasound for the treatment of coronary bifurcation lesions. Am J Cardiol. 2012;109:960–5.

    Article  PubMed  Google Scholar 

  28. Hahn JY, Song YB, Lee SY, et al. Serial intravascular ultrasound analysis of the main and side branches in bifurcation lesions treated with the t-stenting technique. J Am Coll Cardiol. 2009;54:110–7.

    Article  PubMed  Google Scholar 

  29. Park Y, Park HS, Jang GL, et al. Intravascular ultrasound guided recanalization of stumpless chronic total occlusion. Int J Cardiol. 2011;148:174–8.

    Article  PubMed  Google Scholar 

  30. Park JJ, Chae IH, Cho YS, et al. The recanalization of chronic total occlusion leads to lumen area increase in distal reference segments in selected patients: an intravascular ultrasound study. JACC Cardiovasc Interv. 2012;5:827–36.

    Article  PubMed  Google Scholar 

  31. Goto K, Zhao Z, Matsumura M, et al. Mechanisms and patterns of intravascular ultrasound in-stent restenosis among bare metal stents and first- and second-generation drug-eluting stents. Am J Cardiol. 2015;116:1351–7.

    Article  PubMed  Google Scholar 

  32. Ali ZA, Karimi Galougahi K, Nazif T, et al. Imaging- and physiology-guided percutaneous coronary intervention without contrast administration in advanced renal failure: a feasibility, safety, and outcome study. Eur Heart J. 2016;37:3090–5.

    Article  PubMed  Google Scholar 

  33. Lee SY, Shin DH, Kim JS, et al. Intravascular ultrasound predictors of major adverse cardiovascular events after implantation of everolimus-eluting stents for long coronary lesions. Rev Esp Cardiol. 2017;70:88.

    Article  PubMed  Google Scholar 

  34. Song HG, Kang SJ, Ahn JM, et al. Intravascular ultrasound assessment of optimal stent area to prevent in-stent restenosis after zotarolimus-, everolimus-, and sirolimus-eluting stent implantation. Catheter Cardiovasc Interv. 2014;83:873–8.

    Article  PubMed  Google Scholar 

  35. Kang SJ, Cho YR, Park GM, et al. Intravascular ultrasound predictors for edge restenosis after newer generation drug-eluting stent implantation. Am J Cardiol. 2013;111:1408–14.

    Article  CAS  PubMed  Google Scholar 

  36. Hassan AK, Bergheanu SC, Stijnen T, et al. Late stent malapposition risk is higher after drug-eluting stent compared with bare-metal stent implantation and associates with late stent thrombosis. Eur Heart J. 2010;31:1172–80.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Byeong-Keuk Kim .

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Hong, SJ., Jang, Y., Kim, BK. (2018). Clinical Evidence of Intravascular Ultrasound-Guided Percutaneous Coronary Intervention. In: Hong, MK. (eds) Coronary Imaging and Physiology. Springer, Singapore. https://doi.org/10.1007/978-981-10-2787-1_5

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  • DOI: https://doi.org/10.1007/978-981-10-2787-1_5

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