Clinical Applications

  • Yong-Whee BahkEmail author


Understandably, the clinical use of bone scan was much restricted when first introduced in the early 1960s (Fleming et al. (1961) Photoscanning of bone lesions utilizing strontium 85. Radiology 77:635–636). At that time, bone scintigraphy was applied to the diagnosis of cancer metastasis (Fig. 1.2) and fracture (Fig. 3.1). Since then, its scope has been enormously expanded, indeed far beyond the scope originally envisaged. This expansion has been made possible basically by the availability of high-technology gamma camera systems and excellent radiopharmaceuticals and developments in image interpretation science, which have led to ever-increasing clinical demands. Thus, bone scintigraphy has long been established as the most popular nuclear imaging modality, not only for the screening of acute and critical bone and joint disorders but also for standard diagnosis of most skeletal disorders. Lately, the combined use of nuclear angiography, SPECT, and pinhole techniques has greatly increased its diagnostic potential in terms of both sensitivity and specificity.


  1. Bahk YW (1988) Pinhole scintigraphy as applied to bone and joint studies. In: Proceedings of fourth Asia and Oceania congress of nuclear medicine and biology, Taipei, pp 93–95Google Scholar
  2. Bahk YW (1992) Scintigraphic and radiographic imaging of inflammatory bone and joint diseases. In: Pre-congress teaching course of fifth Asia and Oceania congress of nuclear medicine and biology, Jakarta, pp 19–35Google Scholar
  3. Bahk YW, Kim OH, Chung SK (1987) Pinhole collimator scintigraphy in differential diagnosis of metastasis, fracture, and infections of the spine. J Nucl Med 28:447–451PubMedGoogle Scholar
  4. Bahk YW, Chung SK, Kim SH et al (1992) Pinhole scintigraphic manifestations of sternocostoclavicular hyperostosis: report of a case. Korean J Nucl Med 26:155–159Google Scholar
  5. Bahk YW, Park YH, Chung SK et al (1994) Pinhole scintigraphic sign of chondromalacia patellae in older subjects: a prospective assessment with differential diagnosis. J Nucl Med 35:855–862PubMedGoogle Scholar
  6. Fleming WH, McIlraith ID, King R (1961) Photoscanning of bone lesions utilizing strontium 85. Radiology 77:635–636CrossRefPubMedGoogle Scholar
  7. Gillespie PJ, Alexander JL, Edelstyn GA (1975) Changes in 87mSr concentrations in skeletal metastases in patients responding to cyclical combination chemotherapy for advanced breast cancer. J Nucl Med 16:191–193PubMedGoogle Scholar
  8. Hladik WB III, Nigg KK, Rhodes BA (1982) Drug-induced changes in the biologic distribution of radio-pharmaceuticals. Semin Nucl Med 12:184–218CrossRefPubMedGoogle Scholar
  9. Kim JY, Chung SK, Park YH et al (1992) Pinhole bone scan appearance of osteoid osteoma. Korean J Nucl Med 26:160–163Google Scholar
  10. Kim SH, Bahk YW, Chung SK et al (1993a) Pinhole scintigraphic appearance of infantile cortical hyperostosis: “bumpy, segmental tracer uptake”. Korean J Nucl Med 27:319–320Google Scholar
  11. Kim SH, Chung SK, Bahk YW (1993b) Photopenic metastases with septation from papillary thyroid carcinoma: a case report. Korean J Nucl Med 26:305–308Google Scholar

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© Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  1. 1.Department of Nuclear Medicine and RadiologySun Ae General HospitalSeoulSouth Korea

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