Skip to main content
SpringerLink
Log in

Benign Tumors and Tumorous Conditions of the Bone

  • Chapter
  • First Online:
Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases

Abstract

Benign tumors originating from the bone, cartilage, fibrous tissue, vessels, and unknown tissues are one of the most interesting objectives of pinhole scintigraphy. Such tumors include osteoma, osteoid osteoma, osteoblastoma, chondroma, enostosis, chondroblastoma, fibrous cortical defect and nonossifying fibroma, osteochondroma, primary bone cysts, giant cell tumor, and others. Another large group of bone diseases, in the diagnosis of which 99mTc-MDP scanning is beneficial, are tumorous conditions.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 279.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Abdel-Dayem HM, Papademetriou T (1981) Subperiosteal hemorrhage in neurofibromatosis: appearance in scintigraphy. Clin Nucl Med 6:272

    Article  CAS  PubMed  Google Scholar 

  • Azous EM, Saigal G, Rodriguez MM et al (2005) Langerhans’ cell histiocytosis: pathology, imaging and treatment of skeletal involvement. Pediatr Radiol 35:103–115

    Article  Google Scholar 

  • Baek JH, Lee SY, Kim SH et al (1997) Pinhole bone scintigraphic manifestation of fibrous dysplasia. Korean J Nucl Med 31:452–458

    Google Scholar 

  • Bahk YW (1964) Dyschondroplasia with hemangiomata (Maffucci’s syndrome). Radiology 82:407–410

    Article  CAS  PubMed  Google Scholar 

  • Bahk YW, Park YH, Chung SK, Chi JG (1995) Bone pathological correlation of multimodality imaging in Paget’s disease. J Nucl Med 36:1421–1426

    CAS  PubMed  Google Scholar 

  • Becelli R, Carboni A, Gianni C, Alterio A, Renzi G (2002) A rare condition of Hand-Schuller-Christian disease. J Craniofac Surg 13:759–761

    Article  PubMed  Google Scholar 

  • Benli IT, Akalin S, Boysan E et al (1992) Epidemiological, clinical and radiological aspects of osteopoikilosis. J Bone Joint Surg Br 74:504–506

    CAS  PubMed  Google Scholar 

  • Black B, Dooley J, Pyper A, Reed M (1993) Multiple hereditary exostoses. An epidemiologic study of an isolated community in Manitoba Clin Orthop Relat Res 287:212–217

    Google Scholar 

  • Büll U, Keyl W, Meister P et al (1981) Wertigkeit der “Region-of interest”—Technik in der skelettszintigraphischen Diagnostik primärer Knochentumoren. Radiologe 21:46–51

    PubMed  Google Scholar 

  • Conklin JJ, Camargo EE, Wagner H Jr (1981) Bone scan detection of peripheral periosteal leiomyoma. J Nucl Med 22:97

    CAS  PubMed  Google Scholar 

  • Crawford AH Jr, Bagamery N (1986) Osseous manifestations of neurofibromatosis in childhood. J Pediatr Orthop 6:72–88

    Article  PubMed  Google Scholar 

  • Crone-Munzebrock W, Brassow F (1983) A comparison of radiographic and bone scan findings in histiocytosis X. Skelet Radiol 9:170–173

    Article  CAS  Google Scholar 

  • D’Ambrosia R, Ferguson AB Jr (1968) The formation of osteochondroma by epiphyseal cartilage transplantation. Clin Orthop Relat Res 61:103–115

    Article  PubMed  Google Scholar 

  • Dahlin DC, Unni KK (1986a) Osteoid osteoma. In: Bone tumors, 4th edn. Thomas, Springfield

    Google Scholar 

  • Dahlin DC, Unni KK (1986b) Chondroma. In: Bone tumors, 4th edn. Thomas, Springfield

    Google Scholar 

  • Davila JA, Amrami KK, Sundaram M et al (2004) Chondroblastoma of the hands and feet. Skelet Radiol 33:582–587

    Article  Google Scholar 

  • Doyle T, Gunn J, Anderson G et al (2002) Paget’s disease in New Zealand: evidence for declining prevalence. Bone 31:616–619

    Article  CAS  PubMed  Google Scholar 

  • Dupree WB, Enzinger FM (1986) Fibro-osseous pseudo-tumor of the digits. Cancer 58:2103–2109

    Article  CAS  PubMed  Google Scholar 

  • Epstein DA, Levin EJ (1978) Bone scintigraphy in hereditary multiple exostoses. AJR Am J Roentgenol 130:331–333

    Article  CAS  PubMed  Google Scholar 

  • Ferracini R, Zorzan A, Mauro PP, Masse G, Masterson EL (1998) Acetabular osteoblastoma: description of a case. Chir Organi Mov 83:413–417

    CAS  PubMed  Google Scholar 

  • Fitzer PM (1977) Radionuclide angiography—brain and bone imaging in craniofacial dysplasia (CFD): case report. J Nucl Med 18:709–712

    CAS  PubMed  Google Scholar 

  • Focacci C, Lattanzi R, Iadeluca ML, Campioni P (1998) Nuclear medicine in primary bone tumors. Eur J Radiol 27(Suppl 1):S123–S131

    Article  PubMed  Google Scholar 

  • Garrison RC, Unni KK, MeLeod RA et al (1982) Chondrosarcoma arising in osteochondroma. Cancer 49:1890–1897

    Article  CAS  PubMed  Google Scholar 

  • Greenspan A (1995) Bone island (enostosis): current concept—a review. Skelet Radiol 24:111–115

    CAS  Google Scholar 

  • Hall FM, Goldberg RP, Davies JAK et al (1980) Scintigraphic assessment of bone islands. Radiology 135:737–742

    Article  CAS  PubMed  Google Scholar 

  • Helms CA, Hattner RS, Vogler JB III (1984) Radionuclide skeletal survey for pediatric neoplasms. Radiology 151:779–785

    Article  CAS  PubMed  Google Scholar 

  • Hudson TM (1984) Scintigraphy of aneurysmal bone cysts. AJR Am J Roentgenol 142:761–765

    Article  CAS  PubMed  Google Scholar 

  • Humphry A, Gilday DL, Brown RG (1980) Bone scintigraphy in chondroblastoma. Radiology 137:497–499

    Article  CAS  PubMed  Google Scholar 

  • Jaffe HL (1958a) Fibrous cortical defect and non-ossifying fibroma. In: Tumors and tumorous conditions of the bones and joints. Lea & Febiger, Philadelphia, pp 76–91

    Google Scholar 

  • Jaffe HL (1958b) Solitary bone cyst. In: Tumors and tumorous conditions of the bones and joints. Lea & Febiger, Philadelphia, pp 63–75

    Google Scholar 

  • Jee WH, Park YK, McCauley TR et al (1999) Chondroblastoma: MR characteristics with pathologic correlation. J Comput Tomogr 23:721–726

    Article  CAS  Google Scholar 

  • Kaim AH, Hugli R, Bonel HM, Jundt G (2002) Chondroblastoma and clear cell chondrosarcoma: radiological and MRI characteristics with histopathological correlation. Skelet Radiol 31:88–95

    Article  Google Scholar 

  • Keith A (1920) Studies on the anatomical changes which accompany certain growth disorders of the human body. I. The nature of the structural alterations in the disorder known as multiple exostosis. J Anat 54:101–115

    CAS  PubMed  PubMed Central  Google Scholar 

  • Kim JY, Chung SK, Park YH et al (1992) Pinhole bone scintigraphic appearances of osteoid osteoma. Korean J Nucl Med 26:160–163

    Google Scholar 

  • Levine E, De Smet AA, Neff JR et al (1984) Scintigraphic evaluation of giant cell tumor of bone. AJR Am J Roentgenol 143:343–348

    Article  CAS  PubMed  Google Scholar 

  • Lichtenstein L (1972) Osteocartilaginous exostosis in: bone tumors, 4rh edn. Mosby, Saint Louis, pp 17–28

    Google Scholar 

  • Lisbona R, Rosenthall L (1979) Role of radionuclide imaging in osteoid osteoma. AJR Am J Roentgenol 132:77–80

    Article  CAS  PubMed  Google Scholar 

  • McLeod RA, Beabout JW (1973) The roentgenographic features of chondroblastoma. AJR Am J Roentgenol 118:646–471

    Article  Google Scholar 

  • Mirra JM (1989a) Fibrohistiocytic tumors of intramedullary origin. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 692–719

    Google Scholar 

  • Mirra JM (1989b) Aneurysmal bone cyst. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 1267–1331

    Google Scholar 

  • Mirra JM (1989c) Eosinophilic granuloma. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 1023–1045

    Google Scholar 

  • Mirra JM (1989d) Giant cell tumors. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, p 958. (Fig. 13.17)

    Google Scholar 

  • Mirra JM (1989e) Periostitis ossificans. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 1589–1605

    Google Scholar 

  • Mirra JM, Eckhardt JJ (1989) Enchondroma versus chondrosarcoma. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 476–531

    Google Scholar 

  • Mirra JM, Gold RH (1989) Fibrous dysplasia. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 191–226

    Google Scholar 

  • Mungovan JA, Tung GA, Lambiase RE et al (1994) Tc-99 m MDP uptake in osteopoikilosis. Clin Nucl Med 19:6–8

    Article  CAS  PubMed  Google Scholar 

  • Nadel HT, Rossleigh MA (1995) Tumor imaging. In: Treves ST (ed) Pediatric nuclear medicine, 2nd edn. Springer, Berlin Heidelberg New York, pp 496–527

    Chapter  Google Scholar 

  • Neumann RD, Kemp JD, Weiner RE (1995) Gallium-67 imaging for detection of malignant disease. In: Sandler MP et al (eds) Diagnostic nuclear medicine, 3rd edn. Williams and Wilkins, Baltimore, pp 1243–1260

    Google Scholar 

  • Nishio J, Iwasaki H, Soejima O et al (2002) Rapidly growing fibro-osseous pseudotumor of the digits mimicking extraskeletal osteosarcoma. J Orthop Sci 7:410–413

    Article  PubMed  Google Scholar 

  • O’Connell JX, Nanthakumar SS, Nielsen GP, Rosenberg AE (1998) Osteoid osteoma: the uniquely innervated bone tumor. Mod Pathol 11:175–180

    PubMed  Google Scholar 

  • Ochsner PE (1978) Multiple cartilaginous exostoses and neoplastic degeneration: review of the literature. Z Orthop Ihre Grenzgeb 116:369–378

    CAS  PubMed  Google Scholar 

  • Parker BR, Pinckney L, Etcubanas E (1980) Relative efficacy of radiographic and radionuclide bone surveys in the detection of the skeletal lesions of histiocytosis X. Radiology 134:377–380

    Article  CAS  PubMed  Google Scholar 

  • Patel MR, Desai SS (1986) Pseudomalignant osseous tumor of soft tissue: a case report and review of the literature. J Hand Surg [Am] 11:66–70

    Article  CAS  Google Scholar 

  • Pierz KA, Stieber JR, Kusumi K, Dromans JP (2002) Hereditary multiple exostoses: one center’s experience and review of etiology. Clin Orthop Relat Res 401:49–59

    Article  Google Scholar 

  • Pinkas L, Robinson D, Halpern N et al (2001) 99mTc-MIBI scintigraphy in musculoskeletal tumors. J Nucl Med 42:33–37

    CAS  PubMed  Google Scholar 

  • Rambeloarisoa J, el Guedj M, Legeai-Mallet L et al (2002) Hereditary multiple exostoses after 40 years of development: a case report. Rev Med Interne 23:657–664

    Article  CAS  PubMed  Google Scholar 

  • Resnick D, Niwayama G (1988) Enostosis, hyperostosis, and periostitis. In: Resnick D, Niwayama G (eds) Diagnosis of bone and joint disorders, 2nd edn. Saunders, Philadelphia, pp 4073–4139

    Google Scholar 

  • Revel PA (1986) Paget’s disease of bone. In: Pathology of bone. Springer, Berlin Heidelberg New York, pp 147–167

    Chapter  Google Scholar 

  • Roodman GD, Windle JJ (2005) Paget disease of bone. J Clin Invest 115:200–208

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Schaub T, Hahn K (1990) Fibröse dysplasie. In: Brussatis F, Hahn K (eds) Nuklearmedizin in der Orthopädie. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Serafini AN (1976) Paget’s disease of the bone. Semin Nucl Med 6:47–58

    Article  CAS  PubMed  Google Scholar 

  • Shi YR, Wu JY, Hsu YA et al (2002) Mutation screening of the EXT genes in patients with hereditary multiple exostoses in Taiwan. Genet Test 6:237–243

    Article  CAS  PubMed  Google Scholar 

  • Sim FH, Dahlin DC, Beabout JW (1975) Osteoid osteoma: diagnostic problems. J Bone Joint Surg Am 63:154–159

    Article  Google Scholar 

  • Van Nostrand D, Madewell JE, NcNiesh LM et al (1986) Radionuclide bone scanning in giant cell tumor. J Nucl Med 27:329–338

    CAS  PubMed  Google Scholar 

  • Waxman AD (1995) Thallium-201 and technetium-99 m methoxyisobutyl isonitrile in nuclear oncology. In: Sandler MP et al (eds) Diagnostic nuclear medicine, 3rd edn. Williams and Wilkins, Baltimore, pp 1261–1274

    Google Scholar 

  • Westra SJ, van Woerden H, Postma A et al (1983) Radio-nuclide bone scintigraphy in patients with histiocytosis X. Eur J Nucl Med 8:303–306

    Article  CAS  PubMed  Google Scholar 

  • Whyte MP, Murphy WA, Siegel BA (1978) 99mTc-pyrophosphate bone imaging in osteopoikilosis, osteopathia striata, and melorheostosis. Radiology 127:439–443

    Article  CAS  PubMed  Google Scholar 

  • Woldenberg Y, Nash M, Bodner L (2005) Peripheral osteoma of the maxillofacial region. Diagnosis and management: a study of 14 cases. Med Oral Patol Oral Cir Bucal 10(Suppl 2):E139–E142

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Nuclear Medicine and Radiology, Sun Ae General Hospital, Seoul, South Korea

    Yong-Whee Bahk MD, PhD, FACS

Authors
  1. Yong-Whee Bahk MD, PhD, FACS
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yong-Whee Bahk MD, PhD, FACS .

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer Nature Singapore Pte Ltd.

About this chapter

Cite this chapter

Bahk, YW. (2017). Benign Tumors and Tumorous Conditions of the Bone. In: Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-10-2759-8_18

Download citation

  • DOI: https://doi.org/10.1007/978-981-10-2759-8_18

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-2758-1

  • Online ISBN: 978-981-10-2759-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation