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Outcomes of Diabetic Microvascular Complications After Bariatric Surgery

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Abstract

The recent obesity pandemic has been paralleled by an equally dramatic rise in the prevalence of Type 2 Diabetes Mellitus (T2DM), which is of major concern to healthcare providers globally. The metabolic dysregulation characteristic of T2DM gives rise to a host of macrovascular and microvascular complications, specifically cardiovascular, cerebrovascular and peripheral vascular diseases, as well as retinopathy, nephropathy and neuropathy. The mechanisms underlying development of these complications are multifactorial, and incompletely understood. In addition to the direct injurious effect of hyperglycemia, other purported factors include hypertension, the endocrine activity of adipose tissue, the pro-inflammatory state induced by obesity, and the increased intra-abdominal pressure imposed by central adiposity.

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Author information

Authors and Affiliations

  1. Diabetes Complications Research Centre, Conway Institute, University College Dublin, Belfield, Ireland

    Helen M. Heneghan MD, PhD, FRCSI & Carel W. le Roux MBChB, MSc, FRCP, FRCPath, PhD

Authors
  1. Helen M. Heneghan MD, PhD, FRCSI
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  2. Carel W. le Roux MBChB, MSc, FRCP, FRCPath, PhD
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Corresponding author

Correspondence to Carel W. le Roux MBChB, MSc, FRCP, FRCPath, PhD .

Editor information

Editors and Affiliations

  1. Bariatric Division, Upper Gastrointestinal Surgery and Minimal Access Surgery Unit, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu, India

    Saravana Kumar

  2. Bariatric Division, Upper Gastrointestinal Surgery and Minimal Access Surgery Unit, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu, India

    Rachel Maria Gomes

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© 2017 Springer Nature Singapore Pte Ltd.

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Heneghan, H.M., le Roux, C.W. (2017). Outcomes of Diabetic Microvascular Complications After Bariatric Surgery. In: Kumar, S., Gomes, R. (eds) Bariatric Surgical Practice Guide. Springer, Singapore. https://doi.org/10.1007/978-981-10-2705-5_17

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  • DOI: https://doi.org/10.1007/978-981-10-2705-5_17

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-2704-8

  • Online ISBN: 978-981-10-2705-5

  • eBook Packages: MedicineMedicine (R0)

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