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Saccharomyces cerevisiae as a Model for Space Biology

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Yeast Diversity in Human Welfare

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Abstract

Manned spaceflight continues to be in the agenda of most of the countries involved in space research. Development of human settlements in planets and sustainable space ecosystems where crops can be grown and waste recycled are the exciting aims of some of the future space missions. There is considerable concern on the health of the space travelers during long term travel and stay in these unexplored terrains. Astronauts may be exposed to ionizing radiations and weightlessness due to alterations in gravitational force. Studies on astronauts during and after space travel indicate effects on the immune system, cardiovascular system, bone density etc. It is not clearly known how the space missions may influence DNA replication, transcription, and translation and cell division cycle in humans. Information on these will be vital. Experiments on humans and animals could be cumbersome in space. As such use of eukaryotic models like Saccharomyces cerevisiae could be rewarding. The yeast S. cerevisiae is considered as an excellent model for studying eukaryotic biology and has contributed significantly to our understanding of cancer biology and fundamental metabolic processes in humans. In this review, the potential of S. cerevisiae as a model for space biology has been discussed.

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Authors and Affiliations

  1. DST-FIST & UGC-SAP Sponsored School of Life Sciences, SRTM University NAAC Accredited with ‘A’ Grade, Nanded, 431 606, Maharashtra, India

    Shivkrupa Devrao Halbandge & Sankunny Mohan Karuppayil

  2. SRTM University, NAAC Accredited with ‘A’ Grade, Nanded, 431606, Maharashtra, India

    Pandit B. Vidyasagar

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  1. Shivkrupa Devrao Halbandge
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  1. Division of Biological Sciences and Engineering, Netaji Subhas Institute of Technology, Dwarka, Delhi, India

    Tulasi Satyanarayana

  2. Yeast Genetics, Department of Physiology and Cell Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, Gatersleben, Sachsen-Anhalt, Germany

    Gotthard Kunze

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Halbandge, S.D., Vidyasagar, P.B., Karuppayil, S.M. (2017). Saccharomyces cerevisiae as a Model for Space Biology. In: Satyanarayana, T., Kunze, G. (eds) Yeast Diversity in Human Welfare. Springer, Singapore. https://doi.org/10.1007/978-981-10-2621-8_2

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