Abstract
Multidetector row CT (MDCT) is a useful method for correct diagnosis of pancreatic cancers. Multiphase dynamic contrast-enhanced CT with high iodine concentration contrast medium (350 mgI/ml, 100–135 ml) is necessary for evaluation of predictability of pancreatic cancers; dynamic CT requires imaging of at least four phases: early arterial phase, late arterial phase (pancreatic parenchyma phase), venous phase, and equilibrium phase. We evaluate eight factors of the extent of the local spread of pancreatic cancers: intrapancreatic bile duct invasion (CH), duodenal invasion (DU), serosa invasion (S), retroperitoneal invasion (RP), portal venous invasion (PV), arterial invasion (A), perineural invasion (PL), and other organ invasion (OO). Arterial invasion is judged when stenosis or occlusion of arterial lumen or encasement by tumor. Portal invasion is judged contact between the tumor and vessel for ≥1/2 of the vessel circumference. Extrapancreatic neural plexus invasion (PL) is a major determinant of prognosis, and accurate diagnosis is of vital importance in determination of operative method of pancreatic cancers.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Yanaga Y, Awai K, Nakayama Y, et al. Pancreas: patient body weight tailored contrast material injection protocol versus fixed dose protocol at dynamic CT. Radiology. 2007;245(2):475–82.
Fukukura Y, Hamada H, Kamiyama T, et al. Pancreatic adenocarcinoma: analysis of the effect of various concentrations of contrast material. Radiat Med. 2008;26(6):355–61.
Ishigami K, Yoshimitsu K, Irie H, et al. Diagnostic value of the delayed phase image for iso-attenuating pancreatic carcinomas in the pancreatic parenchymal phase on multidetector computed tomography. Eur J Radiol. 2009;69:139–46.
Takeshita K, Furui S, Takada K. Multidetector row helical CT of the pancreas: value of three-dimensional images, two-dimensional reformations, and contrast-enhanced multiphasic imaging. J Hepato-Biliary-Pancreat Surg. 2002;9:576–82.
Nino-Murcia M, Tamm EP, Charnsangavej C, et al. Multidetector-row helical CT and advanced postprocessing techniques for the evaluation of pancreatic neoplasms. Abdom Imaging. 2003;28:366–77.
Gabata T, Kadoya M, Terayama N, et al. Groove pancreatic carcinomas: radiological and pathological findings. Eur Radiol. 2003;13:1679–84.
Lu DS, Reber HA, Krasny RM, et al. Local staging of pancreatic cancer: criteria for unresectability of major vessels as revealed by pancreatic-phase, thin-section helical CT. AJR Am J Roentgenol. 1997;168:1439–43.
Nakayama Y, Yamashita Y, Kadota M, et al. Vascular encasement by pancreatic cancer: correlation of CT findings with surgical and pathologic results. J Comput Assist Tomogr. 2001;25:337–42.
Li H, Zeng MS, Zhou KR, et al. Pancreatic adenocarcinoma: the different CT criteria for peripancreatic major arterial and venous invasion. J Comput Assist Tomogr. 2005;29:170–5.
Mochizuki K, Gabata T, Kosaka K, et al. MDCT findings of extrapancreatic nerve plexus invasion by pancreas head carcinoma: correlation with en bloc pathological specimens and diagnostic accuracy. Eur Radiol. 2010;20:1757–67.
Sakai M, Nakao A, Kaneko T, et al. Para-aortic lymph node metastasis in carcinoma of the head of the pancreas. Surgery. 2005;137:606–11.
Capussotti L, Massucco P, Ribero D, et al. Extended lymphadenectomy and vein resection for pancreatic head cancer: outcomes and implications for therapy. Arch Surg. 2003;138:1316–22.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer Science+Business Media Singapore
About this chapter
Cite this chapter
Gabata, T. (2017). Evaluation of Resectability of Pancreatic Cancer by MDCT. In: Yamaue, H. (eds) Innovation of Diagnosis and Treatment for Pancreatic Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-10-2486-3_3
Download citation
DOI: https://doi.org/10.1007/978-981-10-2486-3_3
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-10-2485-6
Online ISBN: 978-981-10-2486-3
eBook Packages: MedicineMedicine (R0)