CFD Studies on Pressure Drop for Low Reynolds Fluid Flows Across Orifice in Similarly Shaped Microchannel

  • G. Bhuvaneswari
  • Haritha Madhava Reddy
  • Venu Vinod AnanthulaEmail author
Conference paper


Microfluidic devices have great potential in the fields of automation and miniaturization for handling and analysis of fluids. In the present work, study on single-phase flow across orifice in similar shaped microchannel (circular) was carried out under isothermal conditions. CFD Studies were carried out using ANSYS CFX 14.0, varying the fluid velocity (\( U_{m} \)) and orifice contraction ratio (\( \gamma_{do} = d/D \)). Pressure drop characteristics of low Reynolds number Newtonian (water) and non-Newtonian (1.5 % CMC solution, human blood with 45 % haemoglobin and human blood with 70 % haemoglobin) fluids across orifice in circular (\( D \) = 400 µm) were investigated. Simulations were carried out for predicting the orifice pressure drop characteristics for various values of orifice contraction ratio.


Orifice Microchannel Haemoglobin CFD Pressure drop 


  1. Abgrall, P., Gue, A.M.: Lab-on-chip technologies: making a microfluidic network and coupling it into complete microsystems: a review journal. Micromech. Microeng. 17, 15–49 (2007)CrossRefGoogle Scholar
  2. Dessimoz, A., Cavin, L., Renken, A., Kiwi-Minsker, L.: Liquid–liquid two-phase flow patterns and mass transfer characteristics in rectangular glass microreactors. Chem. Eng. Sci. 63(16), 4035–4044 (2008)CrossRefGoogle Scholar
  3. Haeberle, S., Zengerle, R.: Microfluidic platforms for lab-on-a-chip applications. Lab Chip 7, 1094–1110 (2007)CrossRefGoogle Scholar
  4. Jensen, K.F.: Microreaction engineering—is small better? Chem. Eng. Sci. 56, 293–303 (2001)CrossRefGoogle Scholar
  5. Melin, J., Quake, S.R.: Microfluidic large-scale integration: the evolution of design rules for biological automation. Annu. Rev. Biophys. Biomol. Struct. 36, 213–231 (2007)CrossRefGoogle Scholar
  6. Zhao, Y., Chen, G., Yuan, Q.: Liquid-liquid two-phase flow patterns in a rectangular microchannel. AIChE J. 52(12), 4052–4060 (2006)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Singapore 2016

Authors and Affiliations

  • G. Bhuvaneswari
    • 1
  • Haritha Madhava Reddy
    • 1
  • Venu Vinod Ananthula
    • 1
    Email author
  1. 1.Department of Chemical EngineeringNational Institute of TechnologyWarangalIndia

Personalised recommendations