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The History of Hypothermia Therapy for Perinatal Ischemic Brain Injury

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Cell Therapy for Perinatal Brain Injury

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Abstract

Firstly, I mention on pathology of ischemic brain injury, including experimental history of hypothermia. Next, I explain about how clinical trial study starts and proceed to Consensus 2010 in which hypothermia therapy should be recommended for newborns with moderate to severe hypoxic-ischemic encephalopathy (HIE). Next I talk about how hypothermia therapy spreads and could be standardized on the guideline and nationwide online registry system in Japan since Consensus 2010. I explain about some research works about efficacy and criteria of hypothermia therapy. I also introduce unique research about how to control core temperature during transportation in Japan. Finally, I talk about the possibility to start new neuroprotective therapy for newborns with perinatal ischemic brain injury.

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Authors and Affiliations

  1. Department of Pediatrics, Yodogawa Christian Hospital, 1-7-50, Kunijima, Higashi-yodogawaku, Osaka, 533-0024, Japan

    Makoto Nabetani M.D., Ph.D. & Keisuke Kobata M.D.

Authors
  1. Makoto Nabetani M.D., Ph.D.
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  2. Keisuke Kobata M.D.
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Corresponding author

Correspondence to Makoto Nabetani M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Department of Pediatrics, Osaka City University Graduate School of Medicine, Osaka, Japan

    Haruo Shintaku

  2. Department of Pediatrics, University of Tokyo, Tokyo, Japan

    Akira Oka

  3. Department of Pediatrics, Yodogawa Christian Hospital, Osaka, Japan

    Makoto Nabetani

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Nabetani, M., Kobata, K. (2018). The History of Hypothermia Therapy for Perinatal Ischemic Brain Injury. In: Shintaku, H., Oka, A., Nabetani, M. (eds) Cell Therapy for Perinatal Brain Injury. Springer, Singapore. https://doi.org/10.1007/978-981-10-1412-3_9

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  • DOI: https://doi.org/10.1007/978-981-10-1412-3_9

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-1411-6

  • Online ISBN: 978-981-10-1412-3

  • eBook Packages: MedicineMedicine (R0)

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