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Phaeochromocytoma

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Evidence-Based Endocrine Surgery

Abstract

Phaeochromocytomas (PCCs) are tumours that synthesize, store and secrete catecholamines and arise from chromaffin cells of adrenal medulla and extra-adrenal sympathetic ganglia cells. Embryologically, the paraganglia system originates from the neural crest cells, which can differentiate and migrate to form the adrenal medullary chromaffin cells, autonomic ganglion cells and extra-adrenal paraganglionic cells. These cells belong to the amine precursor uptake decarboxylase (APUD) cells. Phaeochromocytoma derives its name from phaios (dusky), chroma (colour) and cytoma (tumour). The term phaeochromocytoma was coined by Pick in 1912. Fränkel was first to report a phaeochromocytoma during autopsy in 1886. The first successful operations for phaeochromocytomas were first reported in 1926 by Cesar Roux in Lausanne, Switzerland, and C.H. Mayo in the United States; but in neither case was the diagnosis established before the operation.

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Author information

Authors and Affiliations

  1. Department of Endocrine Surgery, King George’s Medical University, Lucknow, India

    Anand Kumar Mishra, Kulranjan Singh & Pooja Ramakant

  2. Department of Endocrine Surgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India

    Amit Agarwal

Authors
  1. Anand Kumar Mishra
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  2. Kulranjan Singh
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  3. Pooja Ramakant
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  4. Amit Agarwal
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Editor information

Editors and Affiliations

  1. Division of Endocrine Surgery, National University Hospital, Singapore, Singapore

    Rajeev Parameswaran

  2. Department of Endocrine Surgery, SGPGI Hospital, Lucknow, India

    Amit Agarwal

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Mishra, A.K., Singh, K., Ramakant, P., Agarwal, A. (2018). Phaeochromocytoma. In: Parameswaran, R., Agarwal, A. (eds) Evidence-Based Endocrine Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-10-1124-5_28

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  • DOI: https://doi.org/10.1007/978-981-10-1124-5_28

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-1123-8

  • Online ISBN: 978-981-10-1124-5

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