Abstract
Spatial molecular studies leveraging MALDI IMS during C. difficile infections provides a clear insight into both the mechanisms and effects of colonization on the gastrointestinal environment.
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References
Abt MC, McKenney PT, Pamer EG (2016) Clostridium difficile colitis: pathogenesis and host defence. Nat Rev Microbiol 14:609–620
Fischetti Vincent A, Novick Richard P, Ferretti Joseph J, Portnoy Daniel A, Rood JI (2000) Gram-positive pathogens, pp 551–563
Cornett DS et al (2007) MALDI imaging mass spectrometry: molecular snapshots of biochemical systems. Nat Methods 4:828–833
Sagar NM, Cree IA, Covington JA, Arasaradnam RP (2015) The interplay of the gut microbiome, bile acids, and volatile organic compounds. Gastroenterol Res Pract
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Guiberson, E.R., Wexler, A.G., Perry, W.J., Skaar, E.P., Caprioli, R.M., Spraggins, J.M. (2020). Mapping Molecular Interactions in the Clostridioides difficile Infected Gastrointestinal Tract Using Multimodal Imaging Mass Spectrometry. In: Sindona, G., Banoub, J.H., Di Gioia, M.L. (eds) Toxic Chemical and Biological Agents. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-2041-8_19
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DOI: https://doi.org/10.1007/978-94-024-2041-8_19
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