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Aloysia citriodora Palau

  • Julio Alberto Hurrell
Chapter
Part of the Medicinal and Aromatic Plants of the World book series (MAPW, volume 5)

Abstract

Aloysia citriodora Palau, cedron or lemon verbena, is a South American aromatic species, widespread in North America, Eurasia, and Africa. It is appreciated because of its therapeutic and food (condiment, flavoring) uses. It is also valued for its ornamental, insect repellent properties and sometimes in perfumery. Its popular culinary and medicinal uses have been expanded from Latin America to the rest of the Western world. Its main active constituents are essential oils to which its lemon like aroma and flavor can be attributed. Farther constituents include flavonoids, verbascosides, iridoids heterosides. In folk medicine it is most frequently used to treat gastrointestinal disorders (digestive, antispasmodic, carminative, antidiarrheal), or used as a mild sedative, cardiotonic, febrifuge, analgesic, and antiseptic. Various experimental studies validate different effects, as eupeptic, spasmolytic, antimicrobial, anti-inflammatory, analgesic, hypotensive, among others. Its sedative/anxiolytic activity requires further studies. Of particular interest are its cancer-related effects (antimutagenic, antigenotoxic, and antiangiogenic), and its antioxidant activity linked in various ways to our health.

Keywords

Aloysia citriodora Verbenaceae Cedron Lemon verbena Food and medicinal uses 

References

  1. Abderrahim F, Estrella S, Susín C, Arribas S, González MC, Condezo-Hoyos L (2011) The antioxidant activity and thermal stability of lemon verbena (Aloysia triphylla) infusion. J Med Food 14(5):517–527CrossRefGoogle Scholar
  2. Agah M, Najafian S (2012) Essential oil content and composition of Lippa citriodora as affected by drying method before flowering stages. Eur J Exp Biol 2(5):1771–1777Google Scholar
  3. Ali HFM, El-Beltagi HS, Nasr NF (2011) Evaluation of antioxidant and antimicrobial activity of Aloysia triphylla. Elect J Environ Agric Food Chem 10(8):2689–2699Google Scholar
  4. Alonso J, Desmarchelier C (2005) Plantas medicinales autóctonas de la Argentina. Editorial Lola, Buenos AiresGoogle Scholar
  5. Alonso Paz E, Bassagoda M, Ferreira F (1993) Yuyos: Uso racional de las plantas medicinales. Editorial Fin de Siglo, MontevideoGoogle Scholar
  6. Álvarez Sarmiento XP (2012) Identificación, historia, características y aplicaciones culinarias de cinco plantas aromáticas endémicas de América. Universidad de Cuenca, CuencaGoogle Scholar
  7. Angulo AF, Rosero RA, González MS (2012) Estudio etnobotánico de las plantas medicinales utilizadas por los habitantes del corregimiento de Genoy, Municipio de Pasto, Colombia. Rev Univ Salud 14(2):168–185Google Scholar
  8. Atkins S (2004) Verbenaceae. In: Kubitzki K (ed) The families and genera of vascular plants VII. Springer, Berlin, pp 449–468Google Scholar
  9. Barboza GE, Cantero JJ, Núñez C, Pacciaroni A, Ariza Espinar L (2009) Medicinal plants: a general review and a phytochemical and ethnopharmacological screening of the native Argentine Flora. Kurtziana 34(1–2):7–365Google Scholar
  10. Berardi A (2010) Etnofarmacología gastrointestinal de plantas medicinales argentinas del género Aloysia, familia Verbenaceae: mecanismos de acción y relación con los principios activos. Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La PlataGoogle Scholar
  11. Botta SM (1993) Aloysia. In: Cabrera AL (ed) Flora del la Provincia de Jujuy. Colecc. Cient. Inst. Nac. Tecnol. Agropecu. vol 13, no 9, pp 36–46Google Scholar
  12. Bousta D, Boukhira S, Aafi A, Ghanmi M, El-Mansouri L (2014) Ethnopharmacological Study of anti-diabetic medicinal plants used in the Middle-Atlas region of Morocco (Sefrou region). Int J Pharma Res Health Sci 2(1):75–79Google Scholar
  13. Brant R, Pereira Pinto JE, Vilela Bertolucci S, da Silva A, Brant Albuquerque CJ (2009) Teores do óleo essencial de cidrão [Aloysia triphylla (L’Hérit) Britton (Verbenaceae)] em diferentes horários de colheita e processamentos pós-colheita. Ciênc Agrotec 33:2065–2068CrossRefGoogle Scholar
  14. Burgstaller CH (1968) La vuelta a los vegetales. Dinizo, Buenos AiresGoogle Scholar
  15. Calzada F, Arista R, Pérez H (2010) Effect of plants used in Mexico to treat gastrointestinal disorders on charcoal-gum acacia-induced hyperperistalsis in rats. J Ethnopharmacol 128(1):49–51CrossRefGoogle Scholar
  16. Dellacassa E, Bandoni AL (2003) Hierbaluisa. Aloysia citriodora Palau. Rev Fitoterapia 3(1):19–25Google Scholar
  17. Di Leo Lira P, van Baren CM, Retta D, Bandoni AL, Gil A, Gattuso M, Gattuso S (2008) Characterization of Lemon Verbena (Aloysia citriodora Palau) from Argentina by the Essential Oil. J Essent Oil Res 20(4):350–353CrossRefGoogle Scholar
  18. Di Leo Lira P, van Baren CM, López S, Molina A, Heit C, Viturro C, de Lampasona MP, Catalán CA, Bandoni A (2013) Northwestern Argentina: a center of genetic diversity of lemon verbena (Aloysia citriodora, Verbenaceae). Chem Biodivers 10(2):251–261CrossRefGoogle Scholar
  19. Díaz Fajardo OL (2007) Estudio comparativo de la composición química y evaluación de la actividad antioxidante del aceite esencial de Aloysia triphylla (L’Hér.) Britton, cultivada en tres regiones de Colombia. Universidad Industrial de Santander, BucaramangaGoogle Scholar
  20. Duarte MC, Figueira GM, Sartoratto A, Rehder VL, Delarmelina C (2005) Anti-Candida activity of Brazilian medicinal plants. J Ethnopharmacol 97(2):305–311CrossRefGoogle Scholar
  21. Duarte MC, Leme EE, Delarmelina C, Soares AA, Figueira GM, Sartoratto A (2007) Activity of essential oils from Brazilian medicinal plants on Escherichia coli. J Ethnopharmacol 111(2):197–201CrossRefGoogle Scholar
  22. Elechosa MA (ed) (2009) Manual de recolección sustentable de plantas aromáticas nativas de la región central y noroeste de la Argentina. Inst Nac Tecnol Agropecu, Buenos AiresGoogle Scholar
  23. El-Hawary SS, Yousif MF, Abdel Motaal AA, Abd-Hameed LM (2012) Bioactivities, phenolic compounds and in-vitro propagation of Lippia citriodora Kunth cultivated in Egypt. Bull Fac Pharm Cairo Univ 50(1):1–6CrossRefGoogle Scholar
  24. Eram S, Abbasi Maleki S, Mohammadi Motamed S, Abbasi Maleki M, Hanare Kheliany H (2012) Antidepressant activity of ethanolic extract, chloroform extract and aqueous extract of Aloysia triphylla in the FST and in the TST in male mice. Res Pharm Sci 7(Suppl 5):S856Google Scholar
  25. Fonnegra R, Jiménez SL (2007) Plantas medicinales aprobadas en Colombia, 2nd edn. Editorial Universidad de Antioquía, MedellínGoogle Scholar
  26. Funes L, Férnandez-Arroyo S, Laporta O, Pons A, Roche E, Segura-Carretero A, Fernández-Gutiérrez A, Micol V (2009) Correlation between plasma antioxidant capacity and verbascoside levels in rats after oral administration of lemon verbena extract. Food Chem 117(4):589–598CrossRefGoogle Scholar
  27. Ganjewala D, Gupta AK, Muhury R (2012) An update on bioactive potential of a monoterpene aldehyde citral. J Biol Act Prod Nat 2(4):186–199Google Scholar
  28. Gillij YG, Gleiser RM, Zygadlo JA (2008) Mosquito repellent activity of essential oils of aromatic plants growing in Argentina. Bioresour Technol 99(7):2507–2515CrossRefGoogle Scholar
  29. González Torres DM (2005) Catálogo de plantas medicinales (y alimenticias y útiles) usadas en Paraguay, 2nd edn. Servilibro, AsunciónGoogle Scholar
  30. Hellión-Ibarrola MC, Ibarrola DA, Montalbetti Y, Kennedy ML, Heinichen O, Campuzano M, Tortoriello J, Fernández S, Wasowski C, Marder M, De Lima TC, Mora S (2006) The anxiolytic-like effects of Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) in mice. J Ethnopharmacol 105(3):400–408CrossRefGoogle Scholar
  31. Hellión-Ibarrola MC, Ibarrola DA, Montalbetti Y, Kennedy ML, Heinichen O, Campuzano M, Ferro EA, Alvarenga N, Tortoriello J, De Lima TC, Mora S (2008) The antidepressant-like effects of Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) in mice. Phytomedicine 15(6–7):478–483CrossRefGoogle Scholar
  32. Hernández Cano J, Volpato G (2004) Herbal mixtures in the traditional medicine of Eastern Cuba. J Ethnopharmacol 90(2–3):293–316CrossRefGoogle Scholar
  33. Hieronymus J (1882) Plantas diafóricas. Flora Argentina. G. Kraft, Buenos AiresGoogle Scholar
  34. Hurrell JA, Ulibarri EA, Delucchi G, Pochettino ML (2008) Plantas aromáticas condimenticias. In: Hurrell JA (ed) Biota rioplatense XIII. Editorial Lola, Buenos AiresGoogle Scholar
  35. Hurrell JA, Ulibarri EA, Arenas PM, Pochettino ML (2011) Plantas de Herboristería. Editorial Lola, Buenos AiresGoogle Scholar
  36. Isacchi B, Iacopi R, Bergonzi MC, Ghelardini C, Galeotti N, Norcini M, Vivoli E, Vincieri FF, Bilia AR (2011) Antihyperalgesic activity of verbascoside in two models of neuropathic pain. J Pharm Pharmacol 63(4):594–601CrossRefGoogle Scholar
  37. Koss-Chioino J, Leatherman TL, Greenway C (2003) Medical pluralism in the Andes. Routledge, LondonGoogle Scholar
  38. Lasagni Vitar RM, Reides CG, Ferreira SM, Llesuy SF (2014) The protective effect of Aloysia triphylla aqueous extracts against brain lipid-peroxidation. Food Funct 5(3):557–563CrossRefGoogle Scholar
  39. Lenoir L, Joubert-Zakeyh J, Texier O, Lamaison JL, Vasson MP, Felgines C (2012) Aloysia triphylla infusion protects rats against dextran sulfate sodium-induced colonic damage. J Sci Food Agric 92(7):1570–1572CrossRefGoogle Scholar
  40. Lewis RJ (2007) Citral. In: Hawley’s condensed chemical dictionary, 15th edn. New York: WileyGoogle Scholar
  41. Macía MJ, García E, Vidaurre P (2005) An ethnobotanical survey of medicinal plants commercialized in markets of La Paz and El Alto, Bolivia. J Ethnopharmacol 97(2):337–350CrossRefGoogle Scholar
  42. Madaleno IM, Montero MC (2012) El cultivo urbano de plantas medicinales, su comercialización y usos terapéuticos en la ciudad de Río Cuarto, provincia de Córdoba, Argentina. Cuad Geográficos (Granada) 50(1):63–85Google Scholar
  43. Mamadou G, Meddah B, Limas-Nzouzi N, Ait El Haj A, Bipolo S, Mokondjimobé E, Mahraoui L, Faouzi MA, Ducroc R, Cherrah Y, Eto B (2011) Antispasmodic phytomedicine, from traditional utilization to rational formulation: functional approach. Phytopharmacology 1(3):20–35Google Scholar
  44. Moein M, Zarshenas MM, Etemadfard H (2014) Essential oil composition and total flavonoid content of Aloysia citriodora Palau under different cultivation systems. Int J Plant Anim Environ Sci 4(1):353–358Google Scholar
  45. Mors WB, Rizzini CT, Alvarez P (2000) Medicinal plants of Brazil. Reference, MichiganGoogle Scholar
  46. Múlgura ME, O’Leary N, Rotman A (2012) Verbenaceae. In: Anton AM, Zuloaga FO (eds) Flora Argentina. Flora Vascular de la República Argentina, vol 14, pp 1–220Google Scholar
  47. Muñoz V, Sauvain M, Bourdy G, Arrázola S, Callapa J, Ruiz G, Choque J, Deharo E (2000) A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Alteños Indians. J Ethnopharmacol 71(1–2):123–131CrossRefGoogle Scholar
  48. Muñoz O, Montes M, Wilkomirsky T (2004) Plantas medicinales de uso en Chile, 2nd edn. Editorial Universitaria, Santiago de ChileGoogle Scholar
  49. Nakamura T, Okuyama E, Tsukada A, Yamazaki M, Satake M, Nishibe S, Deyama T, Moriya A, Maruno M, Nishimura H (1997) Acteoside as the analgesic principle of cedron, Lippia triphylla, a Peruvian medicinal plant. Chem Pharm Bull 45(3):499–504CrossRefGoogle Scholar
  50. Natake M, Kanazawa K, Mizuno M, Veno N, Kobayashi T, Danno G, Minamoto S (1989) Herb water-extracts markedly suppress the mutagenicity of Trp-P-2. Agric Biol Chem 53(5):1423–1425Google Scholar
  51. Nematian A, Dalvandi GR, Shariati MA (2014) Effect of planting density and sowing date on the essential oil content and composition of lemon verbena (Lippia citriodora). Int J Biosci 5(2):56–63CrossRefGoogle Scholar
  52. Obon C, Rivera D, Alcaraz F, Attieh L (2014) Beverage and culture. “Zhourat”, a multivariate analysis of the globalization of a herbal tea from the Middle East. Appetite 79:1–10CrossRefGoogle Scholar
  53. Ocazionez RE, Meneses R, Torres FA, Stashenko E (2010) Virucidal activity of Colombian Lippia essential oils on dengue virus replication in vitro. Mem Inst Oswaldo Cruz 105(3):304–309CrossRefGoogle Scholar
  54. Ohno T, Kita M, Yamaoka Y, Imamura S, Yamamoto T, Mitsufuji S, Kodama T, Kashima K, Imanishi J (2003) Antimicrobial activity of essential oils against Helicobacter pylori. Helicobacter 8(3):207–215CrossRefGoogle Scholar
  55. Oliva ML, Carezzano ME, Gallucci MN, Demo MS (2011) Antimycotic effect of the essential oil of Aloysia triphylla against Candida species obtained from human pathologies. Nat Prod Commun 6(7):1039–1043Google Scholar
  56. Ono M, Oda E, Tanaka T, Iida Y, Yamasaki T, Masuoka C, Ikeda T, Nohara T (2008) DPPH radical-scavenging effect on some constituents from the aerial parts of Lippia triphylla. J Nat Med 62(1):101–106CrossRefGoogle Scholar
  57. Osuna Torres L, Tapia Pérez ME, Aguilar Contreras A (2005) Plantas medicinales de la medicina tradicional mexicana para tratar afecciones gastrointestinales. Edicions de la Universitat de Barcelona, BarcelonaGoogle Scholar
  58. Palacios SM, Bertoni A, Rossi Y, Santander R, Urzúa A (2009) Insecticidal activity of essential oils from native medicinal plants of Central Argentina against the house fly, Musca domestica. Parasitol Res 106(1):207–212CrossRefGoogle Scholar
  59. Parodi TV, Cunha MA, Heldwein CG, de Souza DM, Martins ÁC, de Garcia LO, Wasielesky W Jr, Monserrat JM, Schmidt D, Caron BO, Heinzmann B, Baldisserotto B (2012) The anesthetic efficacy of eugenol and the essential oils of Lippia alba and Aloysia triphylla in post-larvae and sub-adults of Litopenaeus vannamei (Crustacea, Penaeidae). Comp Biochem Physiol C Toxicol Pharmacol 155(3):462–468CrossRefGoogle Scholar
  60. Parodi TV, Castagna Vargas AP, Krewer C, Moraes Flores EM, Baldisserotto B, Heinzmann VM, Oliveira J, Secco Popiolski A, Minozzo M (2013) Chemical composition and antibacterial activity of Aloysia triphylla extracts obtained by pressurized CO2 extraction. Braz Arch Biol Technol 56(2):283–292CrossRefGoogle Scholar
  61. Pascual ME, Slowing K, Carretero E, Sánches MD, Villar A (2001) Lippia: traditional uses, chemistry and pharmacology: a review. J Ethnopharmacol 76:201–214CrossRefGoogle Scholar
  62. Pellecuer J, Jacob M, Simeon DM, Dusart G, Attisto M, Barthez M, Gourgas L, Pascal B, Tomei R (1980) Essais d’utilisations d’huiles essentielles de plantes aromatiques Méditerranéennes en odontologie conservatrice. Plant Med Phytother 14:83–98Google Scholar
  63. Pizarro F, Olivares M, Hertramp E, Walter T (1994) Factores que modifican el estado de nutrición del hierro: contenido de taninos de infusiones de hierbas. Arch Latinoam Nutr 44(4):277–280PubMedGoogle Scholar
  64. Pochettino ML, Puentes JP, Buet Costantino F, Arenas PM, Ulibarri EA, Hurrell JA (2012) Functional foods and nutraceuticals in a market of Bolivian immigrants in Buenos Aires (Argentina). Evid Based Complement Altern Med.  https://doi.org/10.1155/2012/320193 CrossRefGoogle Scholar
  65. Pochettino ML, Hurrell JA, Bonicatto MM (2014) Horticultura periurbana: estudios etnobotánicos en huertos familiares y comerciales de la Argentina. Ambienta 107:86–99Google Scholar
  66. Ponce-Monter H, Fernández-Martínez E, Ortiz MI, Ramírez-Montiel ML, Cruz-Elizalde D, Pérez-Hernández N, Cariño-Cortés R (2010) Spasmolytic and anti-inflammatory effects of Aloysia triphylla and citral, in vitro and in vivo studies. J Smooth Muscle Res 46(6):309–319CrossRefGoogle Scholar
  67. Portmann E, Nigro MM, Reides CG, Llesuy S, Ricco RA, Wagner ML, Gurni AA, Carballo MA (2012) Aqueous extracts of Lippia turbinata and Aloysia citriodora (Verbenaceae): assessment of antioxidant capacity and DNA damage. Int J Toxicol 31(2):192–202CrossRefGoogle Scholar
  68. Qnais E, Abu-Safieh K, Abu-Dieyeh MH, Abdulla FA (2009) Antinociceptive effect of two flavonoids from Aloysia triphylla. Jordan J Biol Sci 2(4):167–170Google Scholar
  69. Rachid A, Rabah D, Farid L, Zohra SF, Houcine B, Nacéra B (2012) Ethnopharmacological survey of medicinal plants used in the traditional treatment of diabetes mellitus in the North Western and South Western Algeria. J Med Plants Res 6(10):2041–2050Google Scholar
  70. Ragone MI, Stella M, Conforti P, Volonté MG, Consolini AE (2007) The spasmolytic effect of Aloysia citriodora Palau (South American cedrón) is partially due to its vitexin but not isovitexin on rat duodenus. J Ethnopharmacol 113(2):258–266CrossRefGoogle Scholar
  71. Ragone MI, Stella M, Pastore A, Consolini AE (2010) Sedative and cardiovascular effects of Aloysia citriodora Palau on mice and rats. Lat Am J Pharm 29(1):79–86Google Scholar
  72. Randall RP (2005) A global compendium of weeds, 2nd edn. Department of Agriculture and Food of Western Australia, PerthGoogle Scholar
  73. Rodríguez Quezada MP (2011) Manejo de plantas medicinales en el nororiente amazónico peruano. ECIPerú 8(2):150–157Google Scholar
  74. Rodríguez Vaquero MJ, Tomassini Serravalle LR, Manca de Nadra MC, Strasser de Saad AM (2010) Antioxidant capacity and antibacterial activity of phenolic compounds from Argentinean herbs infusions. Food Control 21(5):779–785CrossRefGoogle Scholar
  75. Rojas LB, Velasco J, Díaz T, Gil Otaiza R, Carmona J, Usubillaga A (2010) Composición química y efecto antibacteriano del aceite esencial de Aloysia triphylla contra patógenos genito-urinarios. Bol Latinoam Caribe Plant Med Aromat 9(1):56–62Google Scholar
  76. Rojas J, Palacios O, Ronceros S (2012) Efecto del aceite esencial de Aloysia triphylla (cedrón) sobre el Trypanosoma cruzi en ratones. Rev Perú Med Exp Salud Públ 29(1):61–68CrossRefGoogle Scholar
  77. Rondina R, Bandoni AL, Coussio JD (2008) Especies medicinales argentinas con potencial actividad analgésica. Dominguezia 24(1):47–69Google Scholar
  78. Salimena FRG, Múlgura ME (2014) Aloysia. In: Lista de Espécies da Flora do Brasil. Jardim Botânico do Rio de Janeiro. Available in: http://www.floradobrasil.jbrj.gov.b. Accessed 27 Dec 2014
  79. Severin C, Bruzzese D, Di Sapio O, Goubileo MG, Gattuso S (2005) Regeneración in vitro de plantas de Aloysia citriodora Palau (Verbenaceae). Rev Invest Fac Ci Agrarias (UNR) 5(8):61–66Google Scholar
  80. Siedo SJ (2007) Systematics of Aloysia (Verbenaceae). ProQuest, Ann ArborGoogle Scholar
  81. Tene V, Malagón O, Vita PV, Vidari G, Armijos C, Zaragoza T (2007) An ethnobotanical survey of medicinal plants used in Loja and Zamora-Chinchipe, Ecuador. J Ethnopharmacol 111(1):63–81CrossRefGoogle Scholar
  82. Toloza AC, Zygadlo J, Biurrun F, Rotman A, Picollo MI (2010) Bioactivity of Argentinean essential oils against permethrin-resistant head lice, Pediculus humanus capitis. J Insect Sci 10:185.  https://doi.org/10.1673/031.010.14145 CrossRefPubMedPubMedCentralGoogle Scholar
  83. Turano FA, Cambi VN (2009) Control de calidad de mezclas de hierbas medicinales que se comercializan como adelgazantes y/o reductoras en Bahía Blanca, Argentina. Lat Am J Pharm 28(1):10–18Google Scholar
  84. Velázquez C, Calzada F, Torres J, Gonzalez F, Ceballos G (2006) Antisecretory activity of plants used to treat gastrointestinal disorders in Mexico. J Ethnopharmacol 103(1):66–70CrossRefGoogle Scholar
  85. Wannmacher L, Fuchs FD, Paoli CL, Fillman HS, Gianlupi A, Lubianca Neto JF, Hassegawa CY, Guimarães FS (1990) Plants employed in the treatment of anxiety and insomnia: II. Effect of infusions of Aloysia triphylla on experimental anxiety in normal volunteers. Fitoperapia 61(5):449–453Google Scholar
  86. Zamorano-Ponce E, Morales C, Ramos D, Sepúlveda C, Cares S, Rivera P, Fernández J, Carballo MA (2006) Anti-genotoxic effect of Aloysia triphylla infusion against acrylamide-induced DNA damage as shown by the comet assay technique. Mutat Res 603(2):145–150CrossRefGoogle Scholar
  87. Zeichen R, De Emilio S, Bindstein E, Chiale C (1997) Efectos sobre el sistema nervioso de Aloysia triphylla (cedrón, yerba Luisa) en ratones. WOCMAP II (Mendoza, Argentina). Abs. p 306Google Scholar
  88. Zeni AL, Zomkowski AD, Dal-Cim T, Maraschin M, Rodrigues AL, Tasca CI (2011) Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway. J Ethnopharmacol 137(1):864–874CrossRefGoogle Scholar
  89. Zihlif M, Afifi F, Muhtaseb R, Al-Khatib S, Abaza I, Naffa R (2012) Screening the antiangiogenic activity of medicinal plants grown and sold in Jordan. Planta Med 78(3):297–301CrossRefGoogle Scholar

Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  • Julio Alberto Hurrell
    • 1
    • 2
  1. 1.Laboratorio de Etnobotánica y Botánica Aplicada (LEBA), Facultad de Ciencias Naturales y MuseoUniversidad Nacional de La PlataLa PlataArgentina
  2. 2.Consejo Nacional de Investigaciones Científicas y TécnicasBuenos Aires RepúblicaArgentina

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