Retroperitoneal Nonchromaffin Paraganglioma

Chapter

Abstract

The paragangliomas, also known as chemodectoma or nonchromaffin paraganglioma tumor, belong to neuroendocrine tumors. They are generally named according to anatomical sites, such as the carotid body tumor and jugular body tumor (referring to paragangliomas located in the carotid body). Paraganglioma is common in adults aged 30–60 years, while patients with retroperitoneal paraganglioma are younger (mostly 30–40 years old) than those with head and neck paraganglioma. Malignant paraganglioma may occur at a younger age. Retroperitoneal paragangliomas are rare tumors, with the incidence equivalent between men and women. They are mostly solitary and sporadic and occasionally multiple. Patients often have a family history. Some cases are accompanied by paragangliomas in other parts of the body or complicated with gastrointestinal stromal tumor (GIST) and pulmonary chondroma as Carney’s triad.

References

  1. Clarke MR, Weyant RJ, Watson CG, et al. Prognostic markers in pheochromocytoma. Hum Pathol. 1998;29(5):522–6.CrossRefGoogle Scholar
  2. Lack EE, Cubilla AL, Woodruff JM, et al. Extra-adrenal paragangliomas of the retroperitoneum: a clinicopathologic study of 12 tumors. Am J Surg Pathol. 1980;4(2):109–20.CrossRefGoogle Scholar
  3. Linnoila RI, Keiser HR, Steinberg SM, et al. Histopathology of benign versus malignant sympathoadrenal paragangliomas: clinicopathologic study of 120 cases including unusual histologic features. Hum Pathol. 1990;21(11):1168–80.CrossRefGoogle Scholar

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© Springer Science+Business Media B.V. 2018

Authors and Affiliations

  1. 1.Peking University International HospitalBeijingChina

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