Abstract
Innate immunity refers to the naturally formed innate immune defensive functions through evolution, which makes up the first line of defense against microbial pathogens. Innate immune system is the natural immune system formed by an organism during a long period of time through evolution, and is mainly composed of the epithelial barrier, the innate immune cells, and the innate immune molecules. It mainly discriminates self from nonself by the pattern recognition mechanism of innate immune system, resulting in the initiation of innate immune responses. The major effector functions of the innate immune response include defense against infectious agents, induction of inflammatory responses, and contribution to the activation, effector functions, and regulation of the adaptive immune responses.
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Sun, H., Sun, C., Tian, Z. (2017). The Innate Immunity. In: Gao, XH., Chen, HD. (eds) Practical Immunodermatology. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-0902-4_2
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DOI: https://doi.org/10.1007/978-94-024-0902-4_2
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