Abstract
Placenta constitutes the barrier between the fetus and the mother that allow the transport of nutrients as well as waste products between the fetus and the mother. The transport, can occur by different ways: simple diffusion, facilitated diffusion and receptor-mediated endocytosis, or by paracellular flow. The way nutrients are transported is influenced by several characteristics namely permeability, nutrient concentration gradients, placental blood flow and metabolism. Physical properties such as elasticity, stiffness and other rheological properties of amniotic membrane and extracellular matrix which are also influenced by the variation of the placenta composition and gestational age.
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References
Damiano A (2011) Review: water channel proteins in the human placenta and fetal membranes. Placenta 32:S207–S211
Hieber A, Corcino D, Motosue J et al (1997) Detection of elastin in the human fetal membranes: proposed molecular basis for elasticity. Placenta 18:301–312
Moore R, Mansour J, Redline R et al (2006) The physiology of fetal membrane rupture: insight gained from the determination of physical properties. Placenta 27:1037–1051
Levkovitz R, Zaretsky U, Gordon Z et al (2013) In vitro simulation of placental transport – part I: biological model of the placental barrier. Placenta 34:699–707
Jansson T, Powell T (2006) Human placental transport in altered fetal growth: does the placenta function as a nutrient sensor? – A review. Placenta 27:91–97
Calvin SE, Oyen ML (2007) Microstructure and mechanics of the chorioamnion membrane with an emphasis on fracture properties. Ann N Y Acad Sci 1101:166–185
Beall M, van den Wijngaard J, van Gemert M, Ross M (2007) Amniotic fluid water dynamics. Placenta 28:816–823
Beall M, van den Wijngaard J, van Gemert M et al (2007) Regulation of amniotic fluid volume. Placenta 28:824–832
Zeuthen T (1995) Molecular mechanisms for passive and active transport of water. Int Rev Cytol 160:99–161
Menjoge ARA, Navatha RS, Asad A et al (2010) Transport and biodistribution of dendrimers across human fetal membranes: implications for intravaginal administration of dendrimers. Biomaterials 31:5007–5021
Levkovitz R, Zaretsky U, Jaffa A et al (2013) In vitro simulation of placental transport – Part II: glucose transfer across the placental barrier model. Placenta 34:708–715
Hutson J, Garcia-Bournissen F, Davis A, Koren G (2011) The human placental perfusion model: a systematic review and development of a model to predict in vivo transfer of therapeutic drugs. Clin Pharmacol Ther 90:67–76
Mathiesen L, Mose T, Mørck TJ et al (2010) Quality assessment of a placental perfusion protocol. Reprod Toxicol 30:138–146
Sastry BR (1999) Techniques to study human placental transport. Adv Drug Deliv Rev 38:17–39
Heaton SJ, Eady JJ, Parker ML et al (2008) The use of BeWo cells as an in vitro model for placental iron transport. Am J Physiol Cell Physiol 295:C1445–C1453
Poulsen MS, Rytting E, Mose T, Knudsen LE (2009) Modeling placental transport: correlation of in vitro BeWo cell permeability and ex vivo human placental perfusion. Toxicol Vitro 23:1380–1386
Lager S, Powell TL (2012) Regulation of nutrient transport across the placenta. J Pregnancy 179827:179827
Jones H, Powell T, Jansson T (2007) Regulation of placental nutrient transport: a review. Placenta 28:763–774
Benson-Martin J, Zammaretti P, Bilic G et al (2006) The Young’s modulus of fetal preterm and term amniotic membranes. Eur J Obstet Gynecol Reprod Biol 128:103–107
Niknejad H, Peirovi H, Jorjani M et al (2008) Properties of the amniotic membrane for potential use in tissue engineering. Eur Cell Mater 15:88–99
Riau AK, Beuerman RW, Lim LS, Mehta JS (2010) Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction. Biomaterials 31:216–225
Pressman EK, Cavanaugh JL, Woods JR (2014) Physical properties of the chorioamnion throughout gestation. Am J Obstet Gynecol 187:672–675
Chen B, Jones RR, Mi S et al (2012) The mechanical properties of amniotic membrane influence its effect as a biomaterial for ocular surface repair. Soft Matter 8:8379
Chua WK, Oyen ML (2009) Do we know the strength of the chorioamnion? A critical review and analysis. Eur J Obstet Gynecol Reprod Biol 144:128–133
Artal R, Sokol R, Neuman M et al (1976) The mechanical properties of prematurely and non-prematurely ruptured membranes: methods and preliminary results. Am J Obstet Gynecol 125:655–659
Artal R, Burgeson R, Hobel C, Hollister D (1979) An in vitro model for the study of enzymatically mediated biomechanical changes in the chorioamniotic membranes. Am J Obstet Gynecol 133:656–659
Oxlund H, Helmig R, Halaburt J, Uldbjerg N (1990) Biomechanical analysis of human chorioamniotic membranes. Eur J Obstet Gynecol Reprod Biol 34:247–255
Helmig R, Oxlund H, Petersen LK, Uldbjerg N (1993) Different biomechanical properties of human fetal membranes obtained before and after delivery. Eur J Obstet Gynecol Reprod Biol 48:183–189
Sillero A, Selivanov VA, Cascante M (2006) Pentose phosphate and calvin cycles: similarities and three-dimensional views. Biochem Mol Biol Educ 34:275–277
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Abrantes, A.M., Casalta-Lopes, J., Botelho, M.F. (2015). Biophysical Properties of Amniotic Membrane. In: Mamede, A., Botelho, M. (eds) Amniotic Membrane. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9975-1_3
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DOI: https://doi.org/10.1007/978-94-017-9975-1_3
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