An Introduction to Impact of Bio-Resonance Technology in Genetics and Epigenetics

  • Mohammad EbrahimiEmail author
  • Sabokhi Sharifov
  • Maryam Salili
  • Larysia Chernosova


According to the WHO, chronic diseases have major economic and social impacts. Despite the increasing scientific efforts to identify the etiology and mechanisms of chronic diseases and to treat them, the prevalence of these diseases in the world is expanding. One concept describing the etiology and mechanisms of chronic diseases is based on “Epigenetic Changes”. Epigenetic changes are permanent changes in gene expression due to Chromatin conformation changes that do not involve any change in DNA sequence. Depending on the time-scale these changes can be persistent through DNA replication. In the eukaryotic nucleus, the nuclear chromatin cluster has electric oscillation capacity. The natural frequency of an oscillating chromatin region is determined by the physical properties of DNA-protein complexes in that region, which can be changed by its epigenetic state and associated protein factors. These changes can be detected using Bio-resonances method and therefore be used to early detection of chronic diseases. It works on the basis of spectral analysis of magnetic fields of living organisms which enables therapist to differentiate normal from abnormal conditions. It is proposed that the electromagnetic waves as epigenetic factors could effect on chromatin dynamic changes and activate or suppress biochemical processes in organism and play a critical role in development or treatment of chronic diseases. This chapter has attempted to demonstrate the opinions of the authors on this issue and its relationship with genetic, epigenetic and also its application in medicine.


Bioresonance therapy Biophoton Epigenetics Genetic 


  1. Adamo AM, Llesuy SF, Pasquini JM, Boveris A (1989) Brain chemiluminescence and oxidative stress in hyperthyroid rats. Biochem J 263:273–277PubMedCentralPubMedGoogle Scholar
  2. Allchin D (2004) Pseudohistory and pseudoscience. Sci Educ 13:179–195CrossRefGoogle Scholar
  3. Amano T, Kobayashi M, Devaraj B, Usa M, Inaba H (1995) Ultraweak biophoton emission imaging of transplanted bladder cancer. Urol Res 23:315–318CrossRefPubMedGoogle Scholar
  4. Andrew AM, Becker R, Ullrich B (1979) Kirlian photography: potential for use in diagnosis. Psychoenergetic Syst 3:47–54Google Scholar
  5. Artem’ey VV, Goldobin AS, Gus’kov LN (1967) Recording the optical emission of a nerve. Biophysics 12:1278–1280Google Scholar
  6. Avijgan M, Avijgan M (2013) Can the primo vascular system (Bong Han duct system) be a basic concept for qi production. Int J Integr Med 1:20Google Scholar
  7. Baehr EK, Fogg LF, Eastman CI (1999) Intermittent bright light and exercise to entrain human circadian rhythms to night work. Am J Physiol-Regul Integr Comp Physiol 277:R1598–R1604Google Scholar
  8. Becker RO (1963) Electron paramagnetic resonance in non-irradiated bone. Nature 28:1304–1305CrossRefGoogle Scholar
  9. Becker RO (1972) Stimulation of partial limb regeneration in rats. Nature 235:109–111CrossRefPubMedGoogle Scholar
  10. Becker RO, Bachman CH, Slaughater WH (1962) Longitudinal direct-current gradients of spinal nerves. Nature 196:675–676CrossRefPubMedGoogle Scholar
  11. Becker RO, Chapin S, Sherry R (1974) Regeneration of the ventricular myocardium in amphibians. Nature 248:145–147CrossRefPubMedGoogle Scholar
  12. Beloussov LV (1997) Life of Alexander G Gurwitsch and his relevant contribution to the theory of morphogenetics field. Int J Dev Biol 41:771PubMedGoogle Scholar
  13. Bird C (1976) What has become of the Rife Microscope. New Age J, 41–47Google Scholar
  14. Blank M, Goodman R (2008) A mechanism for stimulation of biosynthesis by electromagnetic fields: charge transfer in DNA and base pair separation. J Cell Physiol 214:20–26CrossRefPubMedGoogle Scholar
  15. Blank M, Goodman R (2011) DNA is a fractal antenna in electromagnetic fields. Int J Radiat Biol 87:409–415CrossRefPubMedGoogle Scholar
  16. Blokha VV et al (1968) The ultraweak glow of muscles on stimulation. Biophysics 13:1084–1085Google Scholar
  17. Burr HS, Lane CT, Nims LF (1936) A vacuum tube micro-voltmeter for the measurement of bioelectric phenomena. Yale J Biol Med 9(1):65–76Google Scholar
  18. Cadenas E (1980) Spectral analysis of the hydroperoxideinduced chemiluminescence of the perfused lung. FEBS Lett 111:413–418CrossRefPubMedGoogle Scholar
  19. Carlson B (2005) Inventor of dreams. Sci Am 292(3):66CrossRefPubMedGoogle Scholar
  20. Chen T, Guo ZP, Zhang YH, Gao Y (2010) Effect of MORA bioresonance therapy in the treatment of Henoch-Schonlein purpura and influence on serum antioxidant enzymes. J Clin Dermato 139:283–285Google Scholar
  21. Cohen S, Popp FA (1997) Biophoton emission of the human body. J Photochem Photobiol B Biol 40:187–189CrossRefGoogle Scholar
  22. Cottingham WN, Greenwood DA (2007) An introduction to the standard model of particle physics. Cambridge University Press, Cambridge, pp 1–18CrossRefGoogle Scholar
  23. Cremer T, Cremer C (2001) Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nat Rev Genet 2:292–301CrossRefPubMedGoogle Scholar
  24. Dunwell R (2011) SCENAR technology. NZ J Nat Med 3:67–69Google Scholar
  25. Fedoroff NV (2012) Transposable elements, epigenetics, and genome evolution. Science 338:758–767CrossRefPubMedGoogle Scholar
  26. Fröhlich H (1980) The biological effects of microwaves and related questions. Adv Electronics Electron Phys 53:85–152CrossRefGoogle Scholar
  27. Gao X, Xing D (2009) Molecular mechanisms of cell proliferation induced by low power laser irradiation. J Biomed Sci 16:4CrossRefPubMedCentralPubMedGoogle Scholar
  28. Gariaev PP (2001) The DNA-wave Biocomputer.
  29. Gernert D (2008) How to reject any scientific manuscript. J Sci Explor 22:233–243Google Scholar
  30. Gisel HR (2009) In foodture we trust. Xulon, Tallahassee, p. 264 (ISBN 1624199690)Google Scholar
  31. Giuseppe C, Waldemar A (1995) From free radicals to electronically excited species. Free Radic Biol Med 19:103–114CrossRefGoogle Scholar
  32. Gogoleva EF (2001) New approaches to diagnosis and treatment of fibromyalgia in spinal osteo-chondrosis. Ter Arkh 73:40–45PubMedGoogle Scholar
  33. Grass F, Kasper S (2008) Humoral phototransduction: light transportation in the blood, and possible biological effects. Med Hypotheses 71:314–317CrossRefPubMedGoogle Scholar
  34. Grinberg YA (1996) SCENAR therapy: the effectiveness from the point of view of methods of electrotherapy. SCENAR therapy and SCENAR expertise. Compilation Art 2:18–33Google Scholar
  35. Haas M, Peterson D, Hoyer D, Ross G (1994) Muscle testing response to provocative vertebral challenge and spinal manipulation: a randomized controlled trial of construct validity. J Manip Physiol Ther 17:141–148Google Scholar
  36. Helene M, Langevin, Jason A (2002) Relationship of acupuncture points and meridians to connective tissue planes. Anat Rec (NEW ANAT) 269:257–265CrossRefGoogle Scholar
  37. Herrmanna E, Galleb M (2011) Retrospective surgery study of the therapeutic effectiveness of MORA bioresonance therapy with conventional therapy resistant patients suffering from allergies, pain and infection diseases. Eur J Integr Med 3:e237–e244CrossRefGoogle Scholar
  38. Holick MF (2004) Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 80:1678S–1688PubMedGoogle Scholar
  39. Huang S, Sun Z, Fang Y (2005) Klinische Behandlung vom allergischen Schnupfen und Bronchialasthma der Kinder mit dem Bioresonanztherapiegerät. Zhejiang Med J 27:457–458Google Scholar
  40. Hunt VV (1996) Infinite mind: science of the human vibrations of consciousness. Malibu Publishing, Malibu, p 364Google Scholar
  41. Imaizumi S, Kayama T, Suzuki J (1984) Chemiluminescence in hypoxic brain-the first report. Correlation between energy metabolism and free radical reaction. Stroke 15:1061–1065CrossRefPubMedGoogle Scholar
  42. Islamov BI, Balabanova RM, Funtikov VA (2002) Effect of bio-resonance therapy on antioxidant system in lymphocytes in patients with rheumatoid arthritis. Bull Exp Biol Med 134:248–250CrossRefPubMedGoogle Scholar
  43. Kataoka Y, Cui Y, Yamagata A, Niigaki M, Hirohata T, Oishi N, Watanabe Y (2001) Activity-dependent neural tissue oxidation emits intrinsic ultraweak photons. Biochem Biophys Res Commun 285:1007–1011CrossRefPubMedGoogle Scholar
  44. Katelaris CH, Weiner JM, Heddle RJ, Stuckey MS, Yan KW (1991) Vega testing in the diagnosis of allergic conditions. Med J Aust 155:113–114PubMedGoogle Scholar
  45. Kim JD, Choi C, Lim JK (2003) Biophoton emission from rat liver. J Korean Phys 42:427–430Google Scholar
  46. Kobayashi M, Takeda M, Ito K, Kato H, Inaba H (1999a) Two-dimensional photon counting imaging and spatiotemporal characterization of ultraweak photon emission from a rat’s brain in vivo. J Neurosci Methods 93:163–168CrossRefPubMedGoogle Scholar
  47. Kobayashi M, Takeda M, Sato T (1999b) In vivo imaging of spontaneous ultraweak photon emission from a rat’s brain correlated with cerebral energy metabolism and oxidative stress. Neurosci Res 34:103–113CrossRefPubMedGoogle Scholar
  48. Konigsberg UR, Lipton BH, Konigsberg IR (1975) The regenerative response of single mature muscle fibers isolated in vitro. Dev Biol 45:260–275CrossRefPubMedGoogle Scholar
  49. Lee B-C, Bae KH (2011) Network of endocardial vessels. Cardiology J 118:1–7CrossRefGoogle Scholar
  50. Lee BC, Lee HS (2013) Evidence for the fusion of extracellular vesicles with/without DNA to form specific structures in fertilized chicken eggs, mice and rats. Micron 44:468–474CrossRefPubMedGoogle Scholar
  51. Lipton BH (1977) A fine structural analysis of normal and modulated cells in myogenic culture. Dev Biol 60:26–47CrossRefPubMedGoogle Scholar
  52. Lipton BH (1988) The evolving science of chiropractic philosophy. Today’s Chiropr 27:16–19Google Scholar
  53. Lipton BH (1998) Nature, nurture and the power of love. J Prenat Perinat Psychol Health 13:3–10Google Scholar
  54. Lipton BH (2001) Nature, nurture and human development. J Prenat Perinat Psychol Health 16:167–180Google Scholar
  55. Lipton BH (2005a) Insight into cellular consciousness. Bridges ISSEEEM Org 12:5–9Google Scholar
  56. Lipton BH (2005b) The biology of belief: unleashing the power of consciousness, matter and miracles. Mountain of Love Productions, Inc and Elite Books, San RafaelGoogle Scholar
  57. Lipton BH, Jacobson AG (1974) Analysis of normal somite development. Dev Biol 38:73–90CrossRefPubMedGoogle Scholar
  58. Lipton BH, Konigsberg IR (1972) A fine structural analysis of the fusion of myogenic cells. J Cell Biol 53:348–363CrossRefPubMedCentralPubMedGoogle Scholar
  59. Lipton BH, Schultz E (1979) Developmental fate of skeletal muscle satellite cells. Science 205:1292–1924CrossRefPubMedGoogle Scholar
  60. Lipton BH, Bensch KG, Karasek MA (1991) Endothelial cell transdifferentiation: phenotypic characterization. Differentiation 46:117–133CrossRefPubMedGoogle Scholar
  61. Mansfield JW (2005) Biophoton distress flares signal the onset of the hypersensitive reaction. Trends Plant Sci 10:307–309CrossRefPubMedGoogle Scholar
  62. Martin M (1994) Pseudoscience, the paranormal, and science education. Sci Educ 3:357–371CrossRefGoogle Scholar
  63. Mayburov S (2009) Biophoton production and communications. Nanotechnology and nanomaterials. MGOU, Moscow, pp 351–358Google Scholar
  64. Mazhul’ VM, Shcherbin DG (1999) Phosphorescent analysis of lipid peroxidation products in liposomes. Biofizika 44:676–681PubMedGoogle Scholar
  65. McCaig CD, Rajnicek AM (2005) Controlling cell behavior electrically: current views and future potential. Physiol Rev 85:943–978CrossRefPubMedGoogle Scholar
  66. Montgomery S (2003) The rise and fall of a scientific genius: the forgotten story of Royal Raymond Rife. NZ Med J 116:1177Google Scholar
  67. Nakano M (1989) Low-level chemiluminescence during lipid peroxidations and enzymatic reactions. J Biolumin Chemilumin 4:231–240CrossRefPubMedGoogle Scholar
  68. Nienhaus J, Galle M (2006) Placebokontrollierte Studie zur Wirkung einer standardisierten MORA Bioresonanztherapie auf funktionelle Magen-Darm-Beschwerden. Forsch Komplementarmed 13:28–34CrossRefGoogle Scholar
  69. Niggli HJ (1993) Artificial sunlight irradiation induces ultra-weak photon emission in human skin fibroblasts. J Photochem Photobiol 18:281–285CrossRefGoogle Scholar
  70. Niggli HJ, Salvatore T, Lee AA, Scordino A, Musumeci F, Giuseppe P (2005) Laser-ultraviolet-A-induced ultraweak photon emission in mammalian cells. J Biomed Opt 10:24–26CrossRefGoogle Scholar
  71. Nozdrachev AD (1996) Chemical structure of the peripheral autonomic (visceral) reflex. Usp Physiol Sci 27:28–60Google Scholar
  72. Oju M, Gogoleva EF (2000) Outpatient bioresonance treatment of gonarthrosis. Ter Arkh 72:50–53Google Scholar
  73. Peter M (1984) The uses and limitation of acupuncturepoint measurement, German electroacupuncture or electroacupuncture according to Voll. Am J Acupunct 12:33–42Google Scholar
  74. Phelan SE (2008) What is complexity science, really. Emergence 3:120–136CrossRefGoogle Scholar
  75. Piccolino M (1998) Animal electricity and the birth of electrophysiology: the legacy of Luigi Galvani. Brain Res Bull 46:381–407CrossRefPubMedGoogle Scholar
  76. Pihtili A, Cuhhadraroglu C, Kilicaslan Z, Issever H, Erkan F (2009) The effectiveness of bioresonance method in quitting smoking. Clinical report 2009 University Istanbul, Turkey: Department of MedicineGoogle Scholar
  77. Popp FA, Nagl W, Li KH, Scholz W, Weingärtner O, Wolf R (1984) Biophoton emission. New evidence for coherence and DNA as source. Cell Biophys 6:33–52CrossRefPubMedGoogle Scholar
  78. Popp FA, Chang JJ, Herzog A, Yan Z, Yan Y (2002) Evidence of non-classical (squeezed) light in biological systems. Phys Lett A 293:98–102CrossRefGoogle Scholar
  79. Prasad A, Pospısil P (2011) Linoleic acid-induced ultra-weak photon emission from Chlamydomonas reinhardtii as a tool for monitoring of lipid peroxidation in the cell membranes. Plos ONE 6(7):e22345CrossRefPubMedCentralPubMedGoogle Scholar
  80. Prelević R (2011) Quantum-informational medicine and bioresonance technology. Symposium of quantum-informational medicine QIM 2011: acupuncture-based & consciousness-based holistic approaches & techniques, Belgrade, 23-25 Sep 2011Google Scholar
  81. Quickenden TI, Que Hee SS (1974) Weak luminescence from the yeast Sachharomyces-Cervisiae. Biochem Biophys Res Commun 60:764–770CrossRefPubMedGoogle Scholar
  82. Rahlfs VW, Rozehnal A (2008) Wirksamkeit und Verträglichkeit der Bioresonanzbehandlung. Erfahrungsheilkunde 57:462–468CrossRefGoogle Scholar
  83. Rife R (2013) From Wikipedia.
  84. Roland Hans Penner J (1995) The strange life of Nikola Tesla. Kolmogorov-Smirnov Publishing, BasingstokeGoogle Scholar
  85. Rosenow E (1965) Observations with the Rife microscope of filter-passing forms of microorganisms. Science 76:192–193CrossRefGoogle Scholar
  86. Russo VA, Martienssen RA, Riggs AD (1996) Epigenetic mechanisms of gene regulation. Cold Spring Harbor Laboratory Press, Woodbury, pp 5–27Google Scholar
  87. Schimmel HW, Penzer V (1997) Functional medicine: the origin and treatment of chronic diseases, 2nd edn. Alden, Oxford, p 356 (Title No 2639. ISBN 3-7760-1639-6)Google Scholar
  88. Schöni MH, Nikolaizik WH, Schöni-Affolter F (1997) Efficacy trial of bioresonance in children with atopic dermatitis. Int Arch Allergy Immunol 112:238–246CrossRefPubMedGoogle Scholar
  89. Schuller J, Galle M (2007) Untersuchung zur Prüfung der klinischen Wirksamkeit elektronisch abgespeicherter Zahn- und Gelenksnosoden bei Erkrankungen des Rheumatischen Formen-kreises. Forsch Komplemented 14:289–296CrossRefGoogle Scholar
  90. Schwabl H, Klima H (2005) Spontaneous ultraweak photon emission from biological systems and the endogenous light field. Forsch Komplementarmed Klass Naturheilkd 12:84–89CrossRefPubMedGoogle Scholar
  91. Slawinski J, Ezzahir A, Godleweski M (1992) Stress-induced photon emission from perturbed organisms. Experientia 48:1041–1058CrossRefPubMedGoogle Scholar
  92. Soh KS (2011) Current state of research on the primo vascular system. In: Soh KS, Kang KA, Harrison DK (eds) The primo vascular system, its role in cancer and regeneration. Springer, New York, pp 25–39Google Scholar
  93. Soh K-S, Kang KA, Ryu YH (2013) 50 years of Bong-Han theory and 10 years of primo vascular system. Evid-Based Complementary Altern Med. Scholar
  94. Stefanov M, Kim J (2012) Primo vascular system as a new morphofunctional integrated system. J Acupunct Meridian Stud 5(5):193–200. doi:10.1016/j.jams.2012.07.001CrossRefPubMedGoogle Scholar
  95. Sun Y, Wang C, Dai J (2010) Biophotons as neural communication signals demonstrated by in situ biophoton autography. Photochem Photobiol Sci 9:315–322CrossRefPubMedGoogle Scholar
  96. Szent-Gyorgyi A (1960) Introduction to a submolecular biology. Academic, New York, pp 91–103Google Scholar
  97. Szent-Gyorgyi AP (1894) Woods hole marine biological laboratory, Massachusetts. Papers from 1894 to 1995, including photographs, oral histories, published articles, video recordings and lectures. Scholar
  98. Tilbury RN (1992) The effect of stress factors on the spontaneous photon emission from microorganisms. Experientia 48:1030–1104CrossRefPubMedGoogle Scholar
  99. Tilbury RN, Cluickenden TI (1988) Spectral and time dependence studies of the ultraweak bioluminescence emitted by the bacterium Escherichia coli. Photobiochem Photobiophys 47:145–150CrossRefGoogle Scholar
  100. Van Vliet J, Oates NA, Whitelaw E (2007) Epigenetic mechanisms in the context of complex diseases. Cell Mol Life Sci 64:1531–1538CrossRefPubMedGoogle Scholar
  101. Voll R (1974a) Twenty years of electroacupuncture therapy using low-frequency current pulses. Am J Acupunct 3:291–314Google Scholar
  102. Voll R (1974b) Verification of acupuncture by mans of electroacupuncture according to Voll. Am J Acupunct 6:5–15Google Scholar
  103. Yoon YZ (2005) Changes in ultraweak photon emission and heart rate variability of epinephrine-injected rats. Gen Physiol Biophys 24:147–159PubMedGoogle Scholar
  104. Zavitaev YA (1996) SCENAR examples of single SCENAR application. SCENAR therapy and SCENAR expertise. Compilation Art 2:81–82Google Scholar
  105. Zhao Y, Zhan Q (2012) Electric oscillation and coupling of chromatin regulate chromosome packaging and transcription in eukaryotic cells. Theor Biol Med Modelling 9:27CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  • Mohammad Ebrahimi
    • 1
    Email author
  • Sabokhi Sharifov
    • 2
  • Maryam Salili
    • 3
  • Larysia Chernosova
    • 2
  1. 1.The Bio-signal and Immunculus Scientific Group, No4The Research Center for New Technologies in Life Science EngineeringTehranIran
  2. 2.Center of Intellectual Medical Systems IMEDISMoscowRussia
  3. 3.Firoozgar HospitalIran University of Medical SciencesTehranIran

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