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Pseudomonas entomophila: A Versatile Bacterium with Entomopathogenic Properties

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Abstract

Pseudomonas entomophila is unique among Pseudomonas species in being able to activate a systemic immune response in both Drosophila larvae and adults. It has been subsequently shown that oral infections with high doses of this bacterium are highly pathogenic to Drosophila and cause massive destruction of the Drosophila gut epithelium. Besides Drosophila, P. entomophila was able to kill other insects from at least three different orders, suggesting that it has a potentially wide host range and making it a promising model for the study of host pathogen interactions and for the development of bio-control agents against insect pests. In order to unravel the features contributing to P. entomophila’s pathogenic properties, its complete genome was sequenced and genetic screens were performed to identify virulence factors encoded by this bacterium. The aim of this chapter is to review the current knowledge we have on this bacterium with a particular focus on the pathogenesis it induces, its virulence effectors and their genetic regulation.

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Authors and Affiliations

  1. Global Health Institute, EPFL-GHI-SV-UPLEM-, Station 19, Lausanne, Switzerland

    Guennaelle Dieppois & Bruno Lemaitre

  2. Institut de Microbiologie, CHUV, Laboratoire de Diagnostic Moléculaire, 313/IMU/03 Bugnon 48, CH-1011, Lausanne, Switzerland

    Onya Opota

  3. Microbiologia, Departament de Biologia, Edifici Guillem Colom, Universitat de les Illes Balears, Campus UIB, 07122, Palma de Mallorca, Spain

    Jorge Lalucat

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  1. Guennaelle Dieppois
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  2. Onya Opota
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  3. Jorge Lalucat
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  4. Bruno Lemaitre
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Correspondence to Bruno Lemaitre .

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Editors and Affiliations

  1. Estación Experimental del Zaidín, Consejo Superior de Investigaciones, Granada, Spain

    Juan-Luis Ramos

  2. Dept. of Microbiology & Cancer Biology, University of Virginia Health System, Charlottesville, Virginia, USA

    Johanna B. Goldberg

  3. Faculty of Natural Science Division of Cell & Molecular Biology, Imperial College London, London, United Kingdom

    Alain Filloux

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Dieppois, G., Opota, O., Lalucat, J., Lemaitre, B. (2015). Pseudomonas entomophila: A Versatile Bacterium with Entomopathogenic Properties. In: Ramos, JL., Goldberg, J., Filloux, A. (eds) Pseudomonas. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9555-5_2

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