Mouse Liver Transplantation

  • Ulrich StegerEmail author
  • C. Otto
  • I. Klein


Orthotopic mouse liver transplantation (MLTx) is an established model for immunological studies of graft rejection and tolerance induction after solid organ transplantation. Since its introduction in mice by Qian et al. (1991) in 1991, the mouse model has been frequently used to study immunological responses (Qian et al. 1994, 1997, 1996; Li et al. 2001; Klein and Crispe 2006). The model is also suitable to analyze the pathways of hepatic regeneration after prolonged ischemia time and/or partial liver transplantation (Conzelmann et al. 2003; Tian et al. 2011).


Portal Vein Inhalation Anesthesia Anhepatic Phase Partial Liver Transplantation Suprahepatic Vein 
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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  1. 1.Department of Surgery IUniversity of WuerzburgWuerzburgGermany

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