Abstract
The desire to make life is not new. Mythology and history provide numerous examples of this Promethean longing. Materialist and evolutionist scientists over a century ago were convinced of the possibility and even the need to synthesize living beings to advance the knowledge on the nature and origin of life. The premature synthetic biology attempts by Stéphane Leduc and Alfonso L. Herrera reflected the mechanistic ideal in biology of Jacques Loeb. The book “La biologie synthétique” by Leduc (1912) clearly defines the efforts of these pioneers: “Why is it less acceptable to seek how to make a cell than how to make a molecule?” Journalists have presented many advances in biology in the past century as an attempted synthesis of life. Nor is it new, therefore, the fine line which separates the scientific enthusiasm from hype.
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Campos L (2009) That was the synthetic biology that was. In: Schmidt M et al (eds) Synthetic biology: the technoscience and its societal consequences. Springer, Dordrecht, Chap 2, pp 5–21
Cleaves HJ, Lazcano A, Ledesma Mateos I, Negrón-Mendoza A, Peretó J, Silva E (2014) Herrera’s ‘Plasmogenia’ and other collected works: early writings on the experimental study of the origin of life. Springer, New York
Creager ANH (2002) The life of a virus. Tobacco mosaic virus as an experimental model, 1930–1965. The University of Chicago Press, Chicago
Deichmann U (2012) Crystals, colloids, or molecules?: Early controversies about the origin of life and synthetic life. Perspect Biol Med 55:521–542
Fox Keller E (2002) Making sense of life. Explaining biological development with models, metaphors and machines. Harvard University Press, Cambridge
Kornberg A (1989) For the love of enzymes the odyssey of a biochemist. Harvard University Press, Cambridge
Leduc S (1912) La biologie synthétique. A Poinat, Paris
Morange M (2003) Histoire de la biologie moleculaire. La Découverte, Paris
Pauly PJ (1987) Controlling life Jacques Loeb and the engineering ideal in biology. Oxford University Press, New York
Peretó J, Català J (2007) The renaissance of synthetic biology. Biol Theor 2:128–130
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Porcar, M., Peretό, J. (2014). What Was Synthetic Biology?. In: Synthetic Biology. SpringerBriefs in Biochemistry and Molecular Biology, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9382-7_2
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DOI: https://doi.org/10.1007/978-94-017-9382-7_2
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