Systemic Enzyme Therapy: Fact or Fiction? A Review with Focus on Bromelains, Proteolytic Enzymes from the Pineapple Plant

  • Peter MeiserEmail author
  • Zhanjie Xu
  • Gilbert Kirsch
  • Claus Jacob


In this chapter, bromelain, a crude multi-component extract isolated from the stems of the pineapple plant, takes us on a tour through rather unusual therapeutic approaches and pharmacological mechanisms. Bromelain acts on several targets that address edematous, inflammatory, and immunological processes. Therefore, many indications have been treated with or are conceivable to be treated by use of this phytomedicine. Bromelain teaches us that we should keep an open mind toward at first sight exotic therapeutic approaches. A plea for the use of the potential of natural products that are well established in medical therapy for decades or even centuries.


Anti-inflammatory Bromelain Cancer Therapeutic enzymes Myrosinase 


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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Peter Meiser
    • 1
    Email author
  • Zhanjie Xu
    • 1
    • 2
  • Gilbert Kirsch
    • 2
  • Claus Jacob
    • 3
  1. 1.URSAPHARM Arzneimittel GmbHSaarbrueckenGermany
  2. 2.Laboratoire d’Ingénierie Moléculaire et Biochimie PharmacologiqueUniversité de Lorraine 1MetzFrance
  3. 3.Bioorganische ChemieUniversitaet des SaarlandesSaarbrückenGermany

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