Cerium Dioxide CeO2-x and Orthovanadate (Gd0.9Eu0.1VO4) Nanoparticles for Protection of Living Body from X-Ray Induced Damage

  • G. GrygorovaEmail author
  • V. Klochkov
  • Ye. Mamotyuk
  • Yu. Malyukin
Conference paper
Part of the NATO Science for Peace and Security Series A: Chemistry and Biology book series (NAPSA)


The effectiveness of CeO2−x and GdEuVO4 nanoparticles in radioprotection in model animals during radiation exposure has been shown. Nanoparticles were injected per os by two different schemes – once and during 15 days. For the 15-days scheme of GdEuVO4 nanoparticles injection during 30 days of observation the survival of animals irradiated with a dose of 6.0 Gy was 100 %; for ceria it was 90 % for ceria. It was revealed that 7.0 Gy radiation dose is lethal. These results can serve as a motivation to consider inorganic nanoparticles as the basis for new drugs possessing by radioprotective effect.


Cerium Oxide Absorb Dose Rate Cerium Dioxide Radioprotective Effect Free Radical Concentration 
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Copyright information

© Springer Science+Business Media Dordrecht 2016

Authors and Affiliations

  • G. Grygorova
    • 1
    Email author
  • V. Klochkov
    • 1
  • Ye. Mamotyuk
    • 2
  • Yu. Malyukin
    • 1
  1. 1.Institute for Scintillation Materials of NAS of UkraineKharkivUkraine
  2. 2.Grigoriev Institute for Medical Radiology-National Academy of Medical Science of UkraineKharkivUkraine

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