Cerium Dioxide CeO2-x and Orthovanadate (Gd0.9Eu0.1VO4) Nanoparticles for Protection of Living Body from X-Ray Induced Damage
The effectiveness of CeO2−x and GdEuVO4 nanoparticles in radioprotection in model animals during radiation exposure has been shown. Nanoparticles were injected per os by two different schemes – once and during 15 days. For the 15-days scheme of GdEuVO4 nanoparticles injection during 30 days of observation the survival of animals irradiated with a dose of 6.0 Gy was 100 %; for ceria it was 90 % for ceria. It was revealed that 7.0 Gy radiation dose is lethal. These results can serve as a motivation to consider inorganic nanoparticles as the basis for new drugs possessing by radioprotective effect.
KeywordsCerium Oxide Absorb Dose Rate Cerium Dioxide Radioprotective Effect Free Radical Concentration
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