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MVD for Neurogenic Hypertension: A Review

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Abstract

Experimental and clinical arguments to estimate that vascular compression of ventrolateral medulla at level of IX–Xth root entry/exit zone (REZ) seem convincing enough to consider vascular decompression as a possible measure for the treatment of apparently essential HT, likely to be of neurogenic origin.

The main problem remains patient selection, even when high-resolution MRI exploration shows images revealing megadolicho-artery(ies) likely to contribute to the pathology. Are these images of elongated arteries the cause or the consequence of the elevated blood pressure? Beyond such uncertainty, it could however be justified to consider decompressive surgery in the few selected patients in whom, in spite of a well-conducted medical treatment, blood pressure remains high, unstable, and thus life threatening.

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References

  • Barker FG, Jannetta PJ, Bissonette DJ, Shields PT, Larkins MV, Jho HD. Microvascular decompression for hemifacial spasm. J Neurosurg. 1995;82:201–10.

    Article  PubMed  Google Scholar 

  • Frank H, Schobel HP, Heusser K, Geiger H, Fahlbusch R, Naraghi R. Long-term results after microvascular decompression in essential hypertension. Stroke J Cereb Circ. 2001;32:2950–5.

    Article  CAS  Google Scholar 

  • Frank H, Heusser K, Geiger H, Fahlbusch R, Naraghi R, Schobel HP. Temporary reduction of blood pressure and sympathetic nerve activity in hypertensive patients after microvascular decompression. Stroke J Cereb Circ. 2009;40:47–51.

    Article  Google Scholar 

  • Geiger H, Naraghi R, Schobel HP, Frank H, Sterzel RB, Fahlbusch R. Decrease of blood pressure by ventrolateral medullary decompression in essential hypertension. Lancet. 1998;352:446–9.

    Article  CAS  PubMed  Google Scholar 

  • Jannetta PJ, Gendell HM. Clinical observations on etiology of essential hypertension. Surg Forum. 1979;30:431–2.

    CAS  PubMed  Google Scholar 

  • Jannetta PJ, Segal R, Wolfson SK, Dujovny M, Semba A, Cook EE. Neurogenic hypertension: etiology and surgical treatment. II. Observations in an experimental nonhuman primate model. Ann Surg. 1985a;202:253–61.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jannetta PJ, Segal R, Wolfson SK. Neurogenic hypertension: etiology and surgical treatment. I. Observations in 53 patients. Ann Surg. 1985b;201:391–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jianqing C, Sindou M. Treatment of Vago-glossopharyngeal neuralgia with MVD and other neurosurgical procedures. In: Shi-Ting Li, Jun Zhong, Raymond F Sekula jr (editors). Microvascular decompression. Wien: Springer; 2015.

    Google Scholar 

  • Leal PRL, Hermier M, Froment JC, Souza MA, Cristino-Filho G, Sindou M. Preoperative demonstration of the neurovascular compression characteristics with special emphasis on the degree of compression, using high-resolution magnetic resonance imaging: a prospective study, with comparison to surgical findings, in 100 consecutive patients who underwent microvascular decompression for trigeminal neuralgia. Acta Neurochir (Wien). 2010;152:817–25.

    Article  Google Scholar 

  • Leal PRL, Hermier M, Souza MA, Cristino-Filho G, Froment JC, Sindou M. Visualization of vascular compression of the trigeminal nerve with high-resolution 3T MRI: a prospective study comparing preoperative imaging analysis to surgical findings in 40 consecutive patients who underwent microvascular decompression for trigeminal neuralgia. Neurosurgery. 2011;69:15–25; discussion 26.

    Article  PubMed  Google Scholar 

  • Levy EI, Clyde B, McLaughlin MR, Jannetta PJ. Microvascular decompression of the left lateral medulla oblongata for severe refractory neurogenic hypertension. Neurosurgery. 1998;43:1–6; discussion 6–9.

    Article  CAS  PubMed  Google Scholar 

  • Morimoto S, Sasaki S, Takeda K, Furuya S, Naruse S, Matsumoto K, Higuchi T, Saito M, Nakagawa M. Decreases in blood pressure and sympathetic nerve activity by microvascular decompression of the rostral ventrolateral medulla in essential hypertension. Stroke J Cereb Circ. 1999;30:1707–10.

    Article  CAS  Google Scholar 

  • Morise T, Horita M, Kitagawa I, Shinzato R, Hoshiba Y, Masuya H, Suzuki M, Takekoshi N. The potent role of increased sympathetic tone in pathogenesis of essential hypertension with neurovascular compression. J Hum Hypertens. 2000;14:807–11.

    Article  CAS  PubMed  Google Scholar 

  • Naraghi R, Fahlbusch R. Microvascular decompression of the left lateral medulla oblongata for severe refractory neurogenic hypertension. Neurosurgery. 1999;45:955.

    Article  CAS  PubMed  Google Scholar 

  • Segal R, Jannetta PJ, Wolfson SK, Dujovny M, Cook EE. Implanted pulsatile balloon device for simulation of neurovascular compression syndromes in animals. J Neurosurg. 1982;57:646–50.

    Article  CAS  PubMed  Google Scholar 

  • Sindou M. Is there a place for microsurgical vascular decompression of the brainstem for apparent essential blood hypertension? A review. Adv Tech Stand Neurosurg. 2015;42:69–76.

    Article  PubMed  Google Scholar 

  • Sindou M, Fobé JL, Ciriano D, Fischer C. Hearing prognosis and intraoperative guidance of brainstem auditory evoked potential in microvascular decompression. Laryngoscope. 1992;102:678–82.

    Article  CAS  PubMed  Google Scholar 

  • Sindou M, Mahmoudi M, Brînzeu A : Hypertension of neurogenic origin: effect of microvascular decompression of the CNIX-X root entry/exit zone and ventro-lateral medulla on blood pressure in a prospective series of 48 patients with hemifacial spasm associated with essential hypertension. J Neurosurg. 2015:1–9.

    Google Scholar 

  • Smith PA, Meaney JFM, Graham LN, Stoker JB, Mackintosh AF, Mary DASG, Ball SG. Relationship of neurovascular compression to central sympathetic discharge and essential hypertension. J Am Coll Cardiol. 2004;43:1453–8.

    Article  PubMed  Google Scholar 

  • Van Ouwerkerk W, Samii M, Ammitatia M. Essential hypertension in patients with hemifacial spasm or trigeminal neuralgia. Adv Neurosurg. 1989;17:188–93.

    Article  Google Scholar 

  • WHO, ISH Writing Group. World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens. 2003;21:1983–92.

    Article  Google Scholar 

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Correspondence to Marc Sindou MD, DSc .

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Sindou, M., Brînzeu, A. (2016). MVD for Neurogenic Hypertension: A Review. In: Li, ST., Zhong, J., Sekula, Jr., R. (eds) Microvascular Decompression Surgery. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7366-9_10

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  • DOI: https://doi.org/10.1007/978-94-017-7366-9_10

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-017-7365-2

  • Online ISBN: 978-94-017-7366-9

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