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Primordial Germ Cells and Germ Line Stem Cells

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Stem Cells: Basics and Clinical Translation

Part of the book series: Translational Medicine Research ((TRAMERE,volume 1))

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Abstract

Germ cells are a sexual reproductive cell type at any stage from primordial germ cells (PGCs) to mature gametes. Germ line stem cells are important for genetic transmission to future generations. In this review, we focus on female germ line stem cells (FGSCs), spermatogonial stem cells (SSCs), and PGCs. In addition, we summarize current research progress concerning PGC specification, migration, and development, SSC properties, their niche, and fate decisions, as well as the history and current research of FGSCs and their applications.

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  1. Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, No. 800, Dongchuan Road, Minhang District, 200240, Shanghai, China

    Ji Wu, Zhuxia Zheng, Hu Wang, Xingxing Mei, Xingbao Ding & Xiaoyong Li

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  1. Ji Wu
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  2. Zhuxia Zheng
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  3. Hu Wang
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  1. Center of Excellence in Tissue Engineeri, Institute of Basic Medical Sciences School of Basic Medicine, Beijing, China

    Robert Chunhua Zhao

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Wu, J., Zheng, Z., Wang, H., Mei, X., Ding, X., Li, X. (2015). Primordial Germ Cells and Germ Line Stem Cells. In: Zhao, R. (eds) Stem Cells: Basics and Clinical Translation. Translational Medicine Research, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7273-0_1

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