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Non Coding RNA Molecules as Potential Biomarkers in Breast Cancer

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Advances in Cancer Biomarkers

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 867))

Abstract

The pursuit of minimally invasive biomarkers is a challenging but exciting area of research. Clearly, such markers would need to be sensitive and specific enough to aid in the detection of breast cancer at an early stage, would monitor progression of the disease, and could predict the individual patient’s response to treatment. Unfortunately, to date, markers with such characteristics have not made it to the clinic for breast cancer. Past years, many studies indicated that the non-coding part of our genome (the so called ‘junk’ DNA), may be an ideal source for these biomarkers. In this chapter, the potential use of microRNAs and long non-coding RNAs as biomarkers will be discussed.

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Authors and Affiliations

  1. Center for Medical Genetics Ghent, Ghent University, Ghent, Belgium

    Kim De Leeneer & Kathleen Claes

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  1. Kim De Leeneer
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  2. Kathleen Claes
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Correspondence to Kim De Leeneer .

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  1. Institute of Biochemistry and Clinical B, Catholic University School of Medicine, Rome, Italy

    Roberto Scatena

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De Leeneer, K., Claes, K. (2015). Non Coding RNA Molecules as Potential Biomarkers in Breast Cancer. In: Scatena, R. (eds) Advances in Cancer Biomarkers. Advances in Experimental Medicine and Biology, vol 867. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7215-0_16

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