Summary
Qualitative and quantitative variation in pig serum alkaline phosphatase activity is demonstrated. Polymorphic-type patterns of alkaline phosphatase activity are detectable at 1 to 3 weeks of age by starch gel electrophoresis. The patterns seen are due to a variable fast component, which disappears after 3 weeks of age, and appears to be a feature of normal development. Alkaline phosphatase in pre-colostral serum samples exhibits a different electrophoretic mobility to that shown by samples taken after 4 days of age. The change in mobility is not related to colostrum uptake. Quantitative estimations of alkaline phosphatase activity in serum appears to be highest in pre-colostral samples, then rapidly decreases over a period of 4 weeks, and subsequently decreases gradually. In studies of serum alkaline phosphatase levels taken at weekly intervals from seventeen litters for a period of 9 weeks significant differences between litters can be detected.
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References
Gahne, B., 1963, Genetic variation of phosphatase in cattle serum, Nature, 199, 305–306.
Imlah, P., 1964. Inherited variants in Serum ceruloplasmins of the pig, Nature, 203, 658–659.
King, E. H. and Armstrong, A. R., 1934. A convenient method of determining serum and bile phosphatase activity, Canad. Med. Ass. J., 31, 376–381.
Lush, I. E., 1961. Genetic polymorphisms in the egg albumen proteins of the domestic fowl, Nature, 189, 981–984.
Lawrence, S. H., Melnick, P. J. and Weimer, H. E., A species comparison of serum proteins and enzymes by starch gel electrophoresis, 1960. Proc. Soc. Exp. Biol. Med., 105, 572–575.
McCance, R. A. and Widdowson, E. M., 1959. The effect of colostrum on the composition and volume of the plasma of newborn piglets, J Physiol, 145, 547–550.
Poulik, M. D., 1957. Starch gel electrophoresis in a discontinuous system of buffers, Nature, 180, 1477–1479.
Rendel, J. and Stormont, C, 1964. Variants of ovine alkaline serum phosphatases and their association with the R-O blood groups, Proc. Soc. Exp. Biol. N.Y., 115, 853–856.
Smithies, O., 1955. Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults, Biochem. J., 61, 629–641.
Wegger, L and Westergaard, U., 1963. Glutamic oxaloacetic transaminase and alkaline phosphatase in serum of pigs, Annual Report, The Royal Veterin. and Agric. Coll., Inst. F. Sterility Research, 115–126.
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© 1970 Springer Science+Business Media Dordrecht
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Imlah, P. (1970). Ontogenic and Familial Variation in Serum Alkaline Phosphatase of Pigs. In: XIth European Conference on Animal Blood Groups and Biochemical Polymorphism. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-5226-8_52
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DOI: https://doi.org/10.1007/978-94-017-5226-8_52
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