At this meeting 2 years ago we showed that oesophagitis could be created in cats by infusing hydrochloric acid into the animal’s lower oesophagus. This oesophagitis markedly decreased the resting pressure of the lower oesophageal sphincter (normally abbreviated to LES). Furthermore the response of the inflamed LES to various pharmacological stimuli has been described1. This paper reports results of our attempts to prevent the oesophagitis with indomethacin.
- Lower Esophageal Sphincter
- Gastrointestinal Motility
- Mucous Gland
- Lower Esophageal Sphincter Relaxation
- Lower Oesophageal Sphincter
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Brown, F., Beck, B., Fletcher, R., Castell, D., Eastwood, G. (1978). Evidence suggesting prostaglandins mediate lower oesophageal sphincter incompetence associated with inflammation. In: Duthie, H.L. (eds) Gastrointestinal Motility in Health and Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-4389-1_68
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Online ISBN: 978-94-017-4389-1
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