Abstract
In 1923 an article by Ganter[1] was published in which he described intermittent infusion and removal of saline solution into and from the peritoneal cavity of a guinea pig made uremic by ureteral ligation. The urea-N concentration in the fluid was close to the bloodconcentration after a dwell time of 1 h. After several instillations and removals of fluid the animal improved.
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References
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Boen, S.T. (1981). Review of the Clinical Use of Peritoneal Dialysis. In: Nolph, K.D. (eds) Peritoneal Dialysis. Developments in Nephrology, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-2563-7_1
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