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The evolving epidemiology of Helicobacter pylori infection and gastric cancer

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Helicobactor pylori

Abstract

There is now overwhelming epidemiological evidence that populations infected with Helicobacter pylori have an increased risk of non-cardia gastric cancer when compared to uninfected control populations1–4, and the magnitude of the risk increases significantly with the duration of the infection. A recent meta-analysis of 12 nested case-control studies within prospective cohorts reported that H. pylori infection increased the risk of non-cardia gastric cancer 6-fold in populations who have been infected for 10 years or longer, prior to the diagnosis of gastric cancer, suggesting that the younger the acquisition of the infection, the higher the lifetime risk for developing gastric cancer4.

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Authors
  1. J.-Q. Huang
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  2. R. H. Hunt
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Editor information

Editors and Affiliations

  1. Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, L8N 3Z5, Hamilton, Ontario, Canada

    Richard H. Hunt (Professor of Medicine, Director) (Professor of Medicine, Director)

  2. Department of Gastroenterology and Hepatology, Academic Medical Centre, 9 Meibergdreef, 1105 AZ, Amsterdam, The Netherlands

    Guido N. J. Tytgat (Professor) (Professor)

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© 2003 Springer Science+Business Media Dordrecht

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Huang, JQ., Hunt, R.H. (2003). The evolving epidemiology of Helicobacter pylori infection and gastric cancer. In: Hunt, R.H., Tytgat, G.N.J. (eds) Helicobactor pylori. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-1763-2_17

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  • DOI: https://doi.org/10.1007/978-94-017-1763-2_17

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-5778-5

  • Online ISBN: 978-94-017-1763-2

  • eBook Packages: Springer Book Archive

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