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Control of Cardiac Contraction by SR Ca Release and Sarcolemmal Ca Fluxes

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Book cover Excitation-Contraction Coupling and Cardiac Contractile Force

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 122))

Abstract

In the preceding chapters the importance of both Ca current and SR Ca release in E-C coupling have been discussed and it was suggested that Ca from both sources could contribute to the activation of contraction. A major goal of this chapter is to clarify how these two sources of Ca may differ in particular cardiac muscle preparations and under different experimental situations. I will also discuss how the transsarcolemmal Ca fluxes and the SR Ca fluxes interact in a simple framework of overall Ca regulation in cardiac muscle.

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  1. Department of Physiology, Loyola University Medical School, Maywood, USA

    Donald M. Bers (Professor and Chairman)

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© 1993 Springer Science+Business Media Dordrecht

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Bers, D.M. (1993). Control of Cardiac Contraction by SR Ca Release and Sarcolemmal Ca Fluxes. In: Excitation-Contraction Coupling and Cardiac Contractile Force. Developments in Cardiovascular Medicine, vol 122. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-1512-6_8

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  • DOI: https://doi.org/10.1007/978-94-017-1512-6_8

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