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Control of Cardiac Contraction by SR Ca Release and Sarcolemmal Ca Fluxes

  • Donald M. Bers
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 122)

Abstract

In the preceding chapters the importance of both Ca current and SR Ca release in E-C coupling have been discussed and it was suggested that Ca from both sources could contribute to the activation of contraction. A major goal of this chapter is to clarify how these two sources of Ca may differ in particular cardiac muscle preparations and under different experimental situations. I will also discuss how the transsarcolemmal Ca fluxes and the SR Ca fluxes interact in a simple framework of overall Ca regulation in cardiac muscle.

Keywords

Mechanical Restitution Rabbit Ventricle Biphasic Contraction Cardiac Muscle Preparation Rest Potentiation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 1993

Authors and Affiliations

  • Donald M. Bers
    • 1
  1. 1.Department of PhysiologyLoyola University Medical SchoolMaywoodUSA

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