Abstract
Prior to 1980, due to the relatively low incidence of adenocarcinoma of the esophagus and the use of surgery as the primary modality of treatment, information regarding the efficacy of radiation in esophageal adenocarcinoma was limited. Reports in the literature as early as 1948, distinguish adenocarcinoma of the esophagus as a separate entity from the more commonly seen squamous cell carcinoma. A total of 18 cases of esophageal adenocarcinoma were reported in the literature pre-1980, which involved the use of radiation therapy (4 of which were treated preoperatively and 14 treated with radiotherapy alone). These earlier reports largely failed to report on the treatment schema or type of radiation used.
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DeNittis, A.S., Whittington, R., Coia, L. (2001). Multimodality in the Management of Adenocarcinoma of the Esophagus. In: Tilanus, H.W., Attwood, S.E.A. (eds) Barrett’s Esophagus. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0829-6_30
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DOI: https://doi.org/10.1007/978-94-017-0829-6_30
Publisher Name: Springer, Dordrecht
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