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Short Segment Barrett’s Esophagus and Intestinal Metaplasia at the Gastroesophageal Junction

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Barrett’s Esophagus

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Abstract

Barrett’s esophagus is a pathological entity in which the normal squamous mucosa of the lower esophagus is replaced by a metaplastic columnar mucosa. It is accepted to be a consequence of gastro-esophageal reflux disease (GERD) and is premalignant. It has been suggested that in health the normal distal esophagus may be lined by columnar mucosa for a distance of up to 2 cm,1 placing the squamocolumnar junction within the lower esophagus. In clinical practice the landmarks which define the exact termination of the esophagus and the beginning of the stomach have proved difficult to measure with certainty, especially in patients with a hiatus hernia. Consequently, Barrett’s esophagus, was previously only diagnosed when the columnar mucosa extended well into the esophagus, at least 3 cm proximal to the gastro-esophageal junction2. Other investigators have used different criteria ranging from 2 to 5cm3’4. However in the 1980s the accepted international standard for the diagnosis of Barrett’s esophagus was a purely endoscopic diagnosis, made when the squamo-columnar junction (SCJ) was located more than 3cm above the proximal gastric folds.

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Authors
  1. Shaun R. Preston
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  2. Geoffrey W. B. Clark
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Editors and Affiliations

  1. Erasmus University Medical Centre, Rotterdam, The Netherlands

    Hugo W. Tilanus (Professor of Surgery) (Professor of Surgery)

  2. Hope Hospital, Salford, UK

    Stephen E. A. Attwood F.R.C.S. (Consultant Surgeon) (Consultant Surgeon)

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Preston, S.R., Clark, G.W.B. (2001). Short Segment Barrett’s Esophagus and Intestinal Metaplasia at the Gastroesophageal Junction. In: Tilanus, H.W., Attwood, S.E.A. (eds) Barrett’s Esophagus. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0829-6_16

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  • DOI: https://doi.org/10.1007/978-94-017-0829-6_16

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-5860-7

  • Online ISBN: 978-94-017-0829-6

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