Reduced Water for Prevention of Diseases

  • Sanetaka Shirahata
Chapter

Abstract

Although water is a very stable substance, it is easily electrolyzed to produce hydrogen and oxygen molecules. Weak current produces only active hydrogen and hydrogen molecule without production of oxygen molecule. Active hydrogen is so small that almost all minerals adsorbs or absorbs it. These facts prompted us to propose “active hydrogen theory of reduced water”. We have demonstrated that electrolyzed reduced water (ERW) and ground waters such as Hita Tenryosui water in Japan, Nordenau water in Germany, Tracote water in Mexico, which are so called miracle water because of their improving activity on various diseases, are all antioxidative water containing active hydrogen and can scavenge intracellular reactive oxygen species (ROS). Reduced water stimulated glucose uptake into muscle and adipocyte cells as well as insulin. It also stimulated the secretion of insulin from pancreatic beta cells and improved the sugar tolerance damage in type 2 diabetes model mice. Reduced water impaired the tumor phenotypes such as rapid growth, anchorage independent growth in a soft agar, morphology, telomere maintenance, and abilities of invasion, metastasis, and angiogenesis. It activated the cancer immune systems, suppressing the tumor growth in vivo. Reduced water is expected for utilization for prevention and therapy of various diseases.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Benson, J. E. et al. On the reduction of tungsten trioxide accelerated by platinum and water. J. Cat. 5,307-313 (1966).Google Scholar
  2. Hayashi, H.: Water, the Chemistry of Life, Part IV. Explore!, 6, 28–31 (1995).Google Scholar
  3. Hazen, R. M.: Life’s rocky start. Scientific American, 284, 76–85 (2001)PubMedCrossRefGoogle Scholar
  4. Kawada, K.: Dissolution of minerals in relation with the origin of life. Advances in colloid and Interface Science, 71–72, 299–316 (1997).Google Scholar
  5. Kikuchi, K. et al.: Supersaturation phenomena in electrolyzed alkaline water. Abstract book of the 4 “ Functional Water Symposium, pp. 9–10 (1997).Google Scholar
  6. Kim, C. et al Roles of oxidation-reduction potential in electrolyzed oxidizing and chemically modified water for the inactivation of food-related pathogens. J. Food Protection,63, 19–24 (2000).Google Scholar
  7. Levy, R. B. and Boudart, M.: The kinetics and mechanism of spillover. J. Cat., 32, 304–314 (1974).CrossRefGoogle Scholar
  8. Miyamaoto, M. et al.; Effectiveness of acidic oxidative potential water in preventing bacterial infection in islet transplantation. Cell Transplantation,8, 405–411 (1999).Google Scholar
  9. M. Oda et al Electrolyzed and natural reduced water exhibit insulin-like activity on glucose uptake into muscle cells and adipocytes. In: Animal Cell Technology: Products from Cells, Cells as Products, (ed. by A. Bernard et al.), pp. 425–427, Kluwer Academic Publishers (1999).Google Scholar
  10. Shirahata, S. et al Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage. Biochem. Biphys. Res. Commun.,234, 269–274 (1997).Google Scholar
  11. Shirahata, S. et al Electrolyzed reduced water which can scavenge active oxygen species suppresses cell growth and regulates gene expression of animal cells. In `New Developments and New Applications in Animal Cell Technology“, (ed. by O. —W. Merten et al.), Kluwer Academic Publishers, the Netherlands, pp. 93–96 (1998).Google Scholar
  12. Shirahata, S. et al Telomere shortening in cancer cells by electrolyzed-reduced water In `Animal Cell Technology: Challenges for the 21st Century“, (ed. by Ikura et al.), Kluwer Academic Publishers, the Netherlands, pp. 355–359 (1999).Google Scholar
  13. Shirahata, S. et al.: Anti-oxidative Water Improves Diabetes. In: Animal Cell Technology: From Target to Market (ed. by E. Lindner-Olsson et al.), Kluwer Academic Publishers, the Netherlands, in press. Sohal R. S. and Weindruch R.: Oxidative stress, caloric restriction, and aging. Science,273, 59–63 (1996)Google Scholar
  14. Stevens, T. O. and McKinley, J. P.: Lithoautotrophic microbial ecosystems in deep basalt aquifers. Science, 270, 450454 (1995).Google Scholar
  15. Tanaka, N. et al.: The effect of electrolyzed strong acid aqueous solution on hemodialysis equipment. Artificial Organs, 23, 1055–1062 (1999).Google Scholar
  16. Tashiro, H. et al.: Clinical examination of alkaline ion water. Abstract book of Symposium `Electrolyzed functional water in therapy“ in 25 ’ Meeting of Japanese Medical Society, pp. 6–7 (1999).Google Scholar
  17. Toyokuni, S. et al Persistent oxidative stress in cancer. FEBS Lett. 358, 1–3 (1995).Google Scholar
  18. Yahagi, N. et al.: Effect of electrolyzed water on wound healing. Artificial Organs, 24, 984987 (2000).Google Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2002

Authors and Affiliations

  • Sanetaka Shirahata
    • 1
  1. 1.Graduate School of Genetic Resources TechnologyKyushu UniversityFukuokaJapan

Personalised recommendations