Abstract
Human thrombopoietin (hTPO) is a potential therapeutic glycoprotein for the amelioration of thrombocytopenia associated with chemotherapy, irradiation and bone marrow transplantation [1]. The hTPO has been expressed in Chinese hamster ovary (CHO) cells, but its expression level is low (0.7 – 8.5 μg/mL) [2]. To increase the hTPO expression level, culture medium specifically designed for hTPO production needs to be developed.
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References
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© 2003 Springer Science+Business Media Dordrecht
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Sung, Y.H., Lee, G.M. (2003). Development of a Serum-Free Medium Supplemented with Hydrolysate for the Suspension Culture of Recombinant CHO Cells Producing Human Thrombopoietin. In: Yagasaki, K., Miura, Y., Hatori, M., Nomura, Y. (eds) Animal Cell Technology: Basic & Applied Aspects. Animal Cell Technology: Basic & Applied Aspects, vol 13. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0726-8_21
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DOI: https://doi.org/10.1007/978-94-017-0726-8_21
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-6557-5
Online ISBN: 978-94-017-0726-8
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