Abstract
A genomics based approach has been used to identify members of the lysophosphatidic acid acyltransferase (LPAAT) multigene family in Arabidopsis thaliana. Ten putative members of this family containing conserved motifs known to be present in LPAAT and in glycerol-3-phosphate acyltransferase (GPAT) proteins have been identified in the Arabidopsis thaliana genome. These acyltransferases were classified according to their sequence similarity. A member of the first class of genes encodes a LPAAT implicated in glycerolipid biosynthesis in the eukaryotic pathway. The second class contains a gene that encodes an LPAAT of the prokaryotic pathway of lipid biosynthesis in plastids. An additional class containing three genes encodes proteins of unknown function previously undescribed as acyltransferases. The sequence divergence, compartmentalisation and differential expression of members of the gene family are consistent with a specific role for each LPAAT isoform in the production of phosphatidic acid.
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References
Barth PG, Wanders RJ, Vreken P, Janssen EA, Lam J, Baas F. (1999) X-linked cardioskeletal myopathy and neutropenia (Barth syndrome) (MIM 302060). J Inherit Metab Dis 22: 555–67
Bourgis F, Kader J-C, Barret P, Renard M, Robinson D, Robinson C, Delseny M, Roscoe TJ (1999). A plastidial 1-acyl-Glycerol-3-phosphate acyltransferase of Brassica napus. Plant Physiol 120: 913–921
Brown A.P, Coleman J, Tommey AM, Watson MD, Slabas AR. (1994) Isolation and characterisation of a maize cDNA that complements a 1-acyl sn-glycerol-3 phosphate acyltransferase mutant of Escherichia coli and encodes a protein which has similarities to other acyltransferases. Plant Mol Biol. 26: 211–23.
Frentzen M, (1998) Acyltransferases from basic science to modified seed oils. Fett/Lipid 100: 161–166
Hanke C, Wolter FP, Coleman J, Peterek G, Frentzen M. (1994) A plant acyltransferase involved in triacylglycerol biosynthesis complements an Escherichia coli sn-1acylglycerol-3-phosphate acyltransferase mutant. Eur J Biochem. 232: 806–10.
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© 2003 Springer Science+Business Media Dordrecht
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Maisonneuve, S., Guyot, R., Delseny, M., Roscoe, T. (2003). A Multigene Family of Lysophosphatidic Acid Acyltransferases of Arabidopsis Thaliana. In: Murata, N., Yamada, M., Nishida, I., Okuyama, H., Sekiya, J., Hajime, W. (eds) Advanced Research on Plant Lipids. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0159-4_42
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DOI: https://doi.org/10.1007/978-94-017-0159-4_42
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-6210-9
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