Abstract
Some eubacteria produce long chain polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (EPA) and/or docosahexaenoic acid (DHA) by the mechanism differing from the combination of elongation and oxygen-dependent desaturation of fatty acids. Metz et al. (2001) proposed a possible EPA biosynthetic pathway of bacteria, where EPA can be produced by polyketide synthase (PKS)-like enzyme encoded by the EPA gene cluster. Accordingly, a trans double bond at Δ2 of acyl intermediates is isomerized to cis configuration either at Δ3 or at Δ2, when it is not reduced to the C-C bond.
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© 2003 Springer Science+Business Media Dordrecht
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Ootaki, M. et al. (2003). Genes and Pathways Involved in Biosynthesis of Eicosapentaenoic and Docosahexaenoic Acids in Bacteria. In: Murata, N., Yamada, M., Nishida, I., Okuyama, H., Sekiya, J., Hajime, W. (eds) Advanced Research on Plant Lipids. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0159-4_10
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DOI: https://doi.org/10.1007/978-94-017-0159-4_10
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-6210-9
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