Abstract
Protection of genetic material from the damaging effects of environmental pollution is necessary for conservation of the biodiversity. Knowledge on antimutagenesis in order to modulate or mitigate the genotoxic impact of environmental mutagens (genotoxicants), is therefore important. A number of natural as well as synthetic compounds such as ascorbic acid, a-tocopherol, β-carotene, selenium, thiol compounds, butylated hydroxytoluene etc. have been shown to be antimutagenic and therefore exert protection against a variety of genotoxicants (DeFlora & Ramel, 1988). Cells and organisms pre-exposed to a very low non- or sub-toxic dose of a genotoxicant develop inherent adaptive mechanisms enabling themselves to lessen the damaging effects when exposed subsequently to a high toxic dose. This phenomenon is termed as adaptive response. Adaptive response has been shown in bacteria (Samson & Cairns, 1977; Demple & Halbrook, 1983), in higher plants (Rieger et al., 1982) as well as in mammalian cells in vitro (Samson & Schwartz, 1980; Frosina & Abbondandolo, 1985) and in vivo (Farooqi & Kesavan, 1993).
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Panda, B.B., Patra, J., Panda, K.K. (2000). Cadmium Induced Adaptive Response in Plant Cells In vivo — A Possible Model Based on Genotoxicity Studies. In: Yunus, M., Singh, N., de Kok, L.J. (eds) Environmental Stress: Indication, Mitigation and Eco-conservation. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9532-2_16
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DOI: https://doi.org/10.1007/978-94-015-9532-2_16
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