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Naked DNA Helicity Observed by Scanning Tunneling Microscopy

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Scanning Tunneling Microscopy and Related Methods

Part of the book series: NATO ASI Series ((NSSE,volume 184))

Abstract

Uncoated DNA molecules marked with an activated Tris 1-Aziridinyl Phosphine Oxide (TAPO) solution were deposited on gold substrates and imaged in air with high resolution Scanning Tunneling Microscope (STM). Constant current and barrier height STM images show a clear evidence of the helicity of the DNA structure: pitch periodicity ranges between 25 and 34 Å while the average diameter is 20 Å. Molecular structure within a single helix turn is also observed.

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Author information

Authors and Affiliations

  1. Istituto di Struttura della Materia del Consiglio, Nazionale delle Ricerche, via E.Fermi 38, I-00044, Frascati, Italy

    A. Cricenti, A. C. Felici, R. Generosi & E. Gori

  2. Istituto di Medicina Sperimentale del Consiglio, Nazionale delle Ricerche, I-00100, Roma, Italy

    W. Djaczenko

  3. Dipartimento di Fisica, Universita’ di Roma “Tor Vergata”, I-00073, Roma, Italy

    S. Selci & G. Chiarotti

Authors
  1. A. Cricenti
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  2. S. Selci
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  3. A. C. Felici
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  4. R. Generosi
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  5. E. Gori
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  6. W. Djaczenko
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  7. G. Chiarotti
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Editor information

Editors and Affiliations

  1. Institut für Kristallographie und Mineralogie, Universität München, München, Germany

    R. J. Behm

  2. Department of Physics, Universidad Autonoma de Madrid, Madrid, Spain

    N. Garcia

  3. IBM Research Division, Zurich Research Laboratory, Ruschlikon, Switzerland

    H. Rohrer

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© 1990 Springer Science+Business Media Dordrecht

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Cricenti, A. et al. (1990). Naked DNA Helicity Observed by Scanning Tunneling Microscopy. In: Behm, R.J., Garcia, N., Rohrer, H. (eds) Scanning Tunneling Microscopy and Related Methods. NATO ASI Series, vol 184. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-7871-4_19

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  • DOI: https://doi.org/10.1007/978-94-015-7871-4_19

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-4075-6

  • Online ISBN: 978-94-015-7871-4

  • eBook Packages: Springer Book Archive

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