Abstract
In the treatment of reproductive disorders, gonadotrophin preparations and steroid hormones have traditionally had an important role. More recently, the therapeutic potential of synthetic hypothalamic hormone analogues has been established in reproductive and non-reproductive disorders. Due to the complexity of hypothalamic-pituitary-gonadal interactions, the transition from physiology and pharmacology to clinical medicine has sometimes been difficult, but a review of the current results indicates that we can look forward to the future with confidence. The development of potent peptide hormone analogues, new biomedical devices for pulsatile administration and sustained delivery, and sophisticated experimental methods for the evaluation of hypothalamic-pituitary-gonadal function have all contributed to a rapid application of the experimental concepts to clinical reality.
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Sandow, J. (1984). Reproductive releasing hormones — the future. In: Harrison, R.F., Bonnar, J., Thompson, W. (eds) Fertility and Sterility. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-1308-1_4
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DOI: https://doi.org/10.1007/978-94-015-1308-1_4
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-015-1310-4
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