Recent progress in the use of copper IUDs
An increasing world-wide utilization of IUDs represents one of the main events in the field of contraception during the past decade. This is due to many factors, but some are directly related to improvements in design. A major advance was achieved when medicated IUDs were made readily suitable for clinical use. The initial contribution was made by Zipper et al.1 and Doyle and Clewe2, who, simultaneously in 1968, focussed on using the IUD as a carrier for an active antifertility agent: respectively, metallic copper and a synthetic progestin.
KeywordsIntrauterine Device Expulsion Rate Menstrual Blood Loss Insertion Procedure Lower Pregnancy Rate
Unable to display preview. Download preview PDF.
- 1.Zipper, J. A., Medel, M. and Prager, R. (1968). Experimental suppression of fertility by intrauterine copper and zinc in rabbits. In Abstracts of the Sixth World Congress on Fertility and Sterility, Tel Aviv, Israel, May 20–27, p. 154Google Scholar
- 3.Mishell, D. R. (1975). The clinical factor in evaluating IUDs. In Hefnawi, F. and Segal, S. (eds.), Analysis of Intra-uterine Contraception, p. 27. ( Amsterdam: North-Holland )Google Scholar
- 6.El-Badrawi, M. H., Hafez, E. S. E., Barnhart, M. I., Fayad, M. and Shafeek, A. (1981). Ultrastructural changes in human endometrium with copper and non medicated IUDs in utero. Fertil. Steril., 36, 41Google Scholar
- 14.Van der Pas, H., Van Os, W. and Thiery, M. (1983). Performance of multiload IUD models with different copper load. Contracept. Deliv. Syst. (In press)Google Scholar
- 19.Phariss, B. B. (1978). Clinical experience with the intrauterine progesterone contraceptive system. J. Reprod. Med., 20, 155Google Scholar