Current status of human in vitro fertilization

  • R. G. Edwards


The situation today concerning human fertilization in vitro has been transformed beyond recognition. From the early, challenging ideas of 19651 the clinical opportunities of the method were first demonstrated in 1977, when the first embryo implanted after replacement in the uterus; unfortunately, this turned out to be an ectopic pregnancy2. Two years later, the birth of the first children conceived through in vitro fertilization ushered in the beginnings of this new form of clinical medicine for the alleviation of infertility and, perhaps, for the avoidance of inherited disorders by identifying embryos which were afflicted with genetic disorders. Today, the potential of in vitro fertilization as the cure for infertility has been amply proved, as I hope to show in this chapter.


Human Chorionic Gonadotrophin Follicular Fluid Natural Cycle Human Menopausal Gonadotrophin Embryonic Growth 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Edwards, R. G. (1965). Nature, 208, 349 and Lancet, 2, 926Google Scholar
  2. 2.
    Steptoe, P. C. and Edwards, R. G. (1978). Lancet, 2, 366PubMedCrossRefGoogle Scholar
  3. 3.
    Steptoe, P. C. and Edwards, R. G. (1970). Lancet, 1, 683PubMedCrossRefGoogle Scholar
  4. 4.
    Lenz, S. and Lauritsen, J. G. (1982). Fertil. Steril., 38, 673PubMedGoogle Scholar
  5. 5.
    Wikland, M., Nilsson, L., Hansson, R., Hamberger, L. and Janson, P. O. (1983). Fertil Steril., 39, 602Google Scholar
  6. 6.
    Feichtinger, W. and Kemeter, P. (1983). Paper presented at the Conference on the In Vitro Fertilization of the Human Egg, Vienna.Google Scholar
  7. 7.
    Edwards, R. G. and Steptoe, P. C. (1975). J. Reprod. Fertil., Suppl., 22, 121Google Scholar
  8. 8.
    Fowler, R. E., Edwards, R. G., Walters, D. E., Chan, S. T. H. and Steptoe, P. C. (1978). J. Endocrinol., 77, 161PubMedCrossRefGoogle Scholar
  9. 9.
    Edwards, R. G. and Steptoe, P. C. (1983). (In preparation.)Google Scholar
  10. 10.
    Fishel, S. B. and Edwards, R. G. (1982). Human Conception in Vitro. ( London: Academic Press )Google Scholar
  11. 11.
    Edwards, R. G., Purdy, J. M., Steptoe, P. C. and Walters, D. E. (1981). Am. J. Obstet. Gynecol., 141, 408PubMedGoogle Scholar
  12. 12.
    Veeck, L. L., Wortham, J. W. E., Witmyer, J., et al. (1983). Fertil. Steril., 39, 594PubMedGoogle Scholar
  13. 13.
    Fishel, S. B., Edwards, R. G. and Purdy, J. M. (1983). (In preparation)Google Scholar
  14. 14.
    Austin, C. R. (1961). The Mammalian Egg. ( Oxford: Blackwell )Google Scholar
  15. 15.
    Singh, L. and Jones, K. W. (1982). Cell, 28, 205PubMedCrossRefGoogle Scholar

Copyright information

© MTP Press Limited 1984

Authors and Affiliations

  • R. G. Edwards

There are no affiliations available

Personalised recommendations