Clinical use of anti-obsesity agents

Part of the Current Status of Modern Therapy book series (CSMT, volume 2)


It has been estimated that well over 5 million prescriptions were written for the anti-obesity drugs in 1966 in the United Kingdom. Since then, the number of scripts issued has steadily fallen to ‘only’ slightly more than 3 million prescriptions in 1975. This figure would suggest that either the anti-obesity drugs are effective or that they are being extensively over-prescribed. At present, more than one-third of subjects enrolling in a slimming organization will have previously taken at least one anti-obesity agent, and more than three-quarters of subjects referred by general practitioners to a hospital obesity clinic will have previously received drug therapy. It follows that subjects with a weight problem of sufficient concern to make them seek medical attention may, at present, reasonably expect to be prescribed a weight-reducing drug. Certainly most general practitioners prescribe at least one anti-obesity agent, and the majority of patients say that they find such drugs are helpful. Indeed, in a recent survey undertaken by the Consumers’ Association, appetite-suppressant drugs were rated by women slimmers to be the best method of achieving rapid weight loss. However, only 16% of these women considered that dieting with the aid of appetite-reducing pills was a successful method of producing a long-term weight loss1.


Thyroid Hormone Anorexia Nervosa Lactic Acidosis Promote Weight Loss Substantial Weight Loss 
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