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The Biology of Wool and Hair pp 257–273Cite as

Effect of Mutations on the Proteins of Wool and Hair

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Summary

The proteins of wool from Felting Lustre Merino mutant, hair from the naked mutant of mice, and cystine-deficient human hair are compared in each case with the proteins from the normal keratin. The data suggest that genes involved in the regulation of follicle differentiation are often mutated, but this alone may be insufficient to account for all the changes, particularly in the case of the naked mouse hair. Results are presented in support of the concept of heterogeneity of trichothiodystrophy in man.

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Author information

Authors and Affiliations

  1. Division of Wool Technology, C.S.I.R.O., 343 Royal Parade, Parkville, Victoria, 3052, Australia

    J. M. Gillespie & R. C. Marshall

Authors
  1. J. M. Gillespie
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  2. R. C. Marshall
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Editor information

Editors and Affiliations

  1. Department of Biochemistry, University of Adelaide, Australia

    G. E. Rogers

  2. Division of Animal Production, CSIRO, Australia

    P. J. Reis  & K. A. Ward  & 

  3. Division of Protein Chemistry, CSIRO, Australia

    R. C. Marshall

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© 1988 Chapman & Hall, London & New York

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Gillespie, J.M., Marshall, R.C. (1988). Effect of Mutations on the Proteins of Wool and Hair. In: Rogers, G.E., Reis, P.J., Ward, K.A., Marshall, R.C. (eds) The Biology of Wool and Hair. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-9702-1_18

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  • DOI: https://doi.org/10.1007/978-94-011-9702-1_18

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-9704-5

  • Online ISBN: 978-94-011-9702-1

  • eBook Packages: Springer Book Archive

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