Abstract
The discrimination between normal and neoplastic tissues relies essentially on histopathological criteria. Such criteria are major contributors both to the classification of neoplastic lesions and to the establishment of diagnostic and prognostic evaluations of the neoplastic disease. More recently, other complementary approaches have been sought which may provide a finer assessment of the behavioral potential of the neoplastic lesion and have included the application of scanning electron microscopy (SEM). There is particular need for marker systems which can lead to the recognition and characterization of early lesions preceding the development of overt tumors and which, in epithelial tissues, can reliably distinguish between histologically similar, though biologically different, lesions that may be forerunners of carcinoma in situ (Symposium, 1976). A further need is to predict with certainty the future behavior of residual epithelium following removal of the overt lesion.
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Hodges, G.M., Kenemans, P. (1982). Diagnostic applications to oncology. In: Hafez, E.S.E., Kenemans, P. (eds) Atlas of Human Reproduction. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-8140-2_34
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DOI: https://doi.org/10.1007/978-94-011-8140-2_34
Publisher Name: Springer, Dordrecht
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