Abstract
There is increasing evidence that the human HLA system contains immune response (Ir) determinants that control immune responsiveness towards a variety of antigens. In immunopathic disorders the Ir gene seems to be in linkage disequilibrium preferentially with the B and D loci of the HLA system. In coeliac disease compared to a normal population there is a significantly increased frequency of HLA-B8 and DRw3.
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Rossipal, E. (1981). On the Association of Coeliac Disease with Allergic Disorders. A Study of Family Histories of 110 Families with One or Two Children with Coeliac Disease. In: McConnell, R.B. (eds) The Genetics of Coeliac Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-8114-3_12
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DOI: https://doi.org/10.1007/978-94-011-8114-3_12
Publisher Name: Springer, Dordrecht
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