The Immunobiology of Chorionic Gonadotrophin

  • J. P. Hearn


The last 10 years have seen a revolution in our understanding of the structure and functions of chorionic gonadotrophin (CG). Until the early seventies it was thought to be a glycoprotein hormone restricted to pregnancy in primates. It was known to be secreted by the trophoblast and assumed to be a major component of the luteotrophic stimulus that supports the corpus luteum of primates until the luteoplacental shift is completed1–3. While this role in early pregnancy, backed by a great deal of circumstantial evidence, is still accepted, we are now fairly certain that the hormone is restricted neither to pregnancy nor to primates.


Antibody Titre Early Pregnancy Corpus Luteum Chorionic Gonadotrophin Passive Immunization 
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© MTP Press Limited 1980

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  • J. P. Hearn

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